{"id":"W2112800304","doi":"10.1101/cshperspect.a016808","title":"Ubiquitin-Dependent Sorting in Endocytosis","year":2014,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":222,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"Endocytic cycle; Ubiquitin; Endosome; Endocytosis; Cell biology; Biology; Protein Sorting Signals; Internalization; Lysosome; Deubiquitinating enzyme; Protein targeting; Proteolysis; Membrane protein; Biochemistry; Membrane; Signal peptide; Peptide sequence; Intracellular; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008129641,0.001213945,0.001336717,0.002032961,0.0006255506,0.001598907,0.001276258,0.00207548,0.004627558],"category_scores_gemma":[0.0004656383,0.0003561898,0.0004951811,0.00239947,0.001428866,0.002568512,0.001255237,0.002738419,0.006113445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002290575,"about_ca_system_score_gemma":0.001694732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001472304,"about_ca_topic_score_gemma":0.002074999,"domain_scores_codex":[0.9997516,0.00003364055,0.00002582727,0.00004015624,0.0001109337,0.0000377995],"domain_scores_gemma":[0.9998372,0.00004272228,0.00001880437,0.000009828017,0.00005818209,0.00003327897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006813582,0.00006012661,0.0001269155,0.008056933,0.00005270759,0.0003346539,0.00009322811,0.0005086833,0.002179191,0.03316496,0.09686682,0.8584876],"study_design_scores_gemma":[0.000006619752,0.00001679529,0.0001927424,0.0006911936,0.0000110856,0.0004522017,0.00002137993,0.00004181961,0.0001931638,0.004720466,0.9936446,0.000008083284],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006942321,0.9951686,0.0002010527,0.0004710046,0.0005488545,0.000007478932,0.00001336664,0.00001254113,0.003507783],"genre_scores_gemma":[0.0009814714,0.9946479,0.0002623841,0.0005709492,0.0003619791,0.000009183249,0.00002810883,0.000003401687,0.003134585],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004627558,"threshold_uncertainty_score":0.01661938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02452941274946741,"score_gpt":0.3102169209355499,"score_spread":0.2856875081860825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}