{"id":"W2112805640","doi":"10.1523/jneurosci.5024-05.2006","title":"α5GABA <sub>A</sub> Receptors Mediate the Amnestic But Not Sedative-Hypnotic Effects of the General Anesthetic Etomidate","year":2006,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Mount Sinai Hospital; Women's College Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Etomidate; Anesthetic; Amnesia; GABAA receptor; Sedative; Hippocampal formation; Pharmacology; Hypnotic; Long-term potentiation; Neuroscience; Inhibitory postsynaptic potential; Anesthesia; Receptor; Medicine; Psychology; Internal medicine; Propofol; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140039,0.000444026,0.0002248254,0.0001260396,0.0001092822,0.0003112229,0.0002467179,0.0002715295,0.001106067],"category_scores_gemma":[0.0001578086,0.0001737405,0.0003100176,0.00005008556,0.0002649831,0.0003597203,0.0001618518,0.0006219335,0.0006045002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002759979,"about_ca_system_score_gemma":0.0001587196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000719951,"about_ca_topic_score_gemma":0.0009166232,"domain_scores_codex":[0.9998946,0.00001366071,0.00001484879,0.0000143346,0.000022089,0.00004039422],"domain_scores_gemma":[0.9998796,0.00001109521,0.00005271311,0.00001239644,0.00001350364,0.00003074286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003878693,0.00002031269,0.0002959117,0.0000258271,0.00000883563,0.00007873136,0.00001066251,0.00003995642,0.9978277,0.0001929812,0.00003435487,0.001076811],"study_design_scores_gemma":[0.0001050749,0.0008733175,0.02416845,0.00002581579,0.00009902823,0.0007697502,0.0001137677,0.001499406,0.9692107,0.0002503476,0.00287603,0.000008329034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950621,0.001448067,0.001834836,0.0001090316,0.00003058878,0.00001578842,0.0001334052,0.00004542385,0.001320711],"genre_scores_gemma":[0.9953117,0.0013026,0.001020439,0.00008162107,0.00001743665,0.00001981822,0.0001649388,0.00001502699,0.002066327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001106067,"threshold_uncertainty_score":0.003700137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02741887930718662,"score_gpt":0.298518033996748,"score_spread":0.2710991546895614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}