{"id":"W2112856131","doi":"","title":"A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.","year":2002,"lang":"en","type":"article","venue":"PubMed","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"","keywords":"Diphtheria toxin; Myeloid leukemia; Progenitor cell; Interleukin 3; Leukemia; Biology; Molecular biology; Immunology; Nod; Bone marrow; Andrology; Stem cell; Medicine; CD8; Immune system; Toxin; Endocrinology; Interleukin 21; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646172,0.0002257267,0.0002191938,0.0001214998,0.00009125229,0.0002443306,0.0001253979,0.000216074,0.000561551],"category_scores_gemma":[0.0001398325,0.00009267071,0.000143541,0.0001679476,0.0002144577,0.0001719845,0.0001532539,0.0004691441,0.0001965854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002382723,"about_ca_system_score_gemma":0.000183489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002870648,"about_ca_topic_score_gemma":0.0003935428,"domain_scores_codex":[0.9998393,0.00002617391,0.00001460021,0.00003285593,0.00004813636,0.00003899507],"domain_scores_gemma":[0.9998842,0.00003654762,0.00002842927,0.00001598706,0.000007880486,0.00002688943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000162673,0.00001782421,0.0003728,0.00001851372,0.000002886377,0.00002933868,0.00001126668,0.00005856854,0.9981477,0.00003935873,0.00001830359,0.001120787],"study_design_scores_gemma":[0.00003084426,0.001432577,0.01034635,0.000004948979,0.00002557732,0.0008719451,0.00001943411,0.0007863118,0.9846059,0.00005519794,0.001817178,0.000003659849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974397,0.0007019868,0.001067929,0.00002336818,0.000007695537,0.00001632411,0.0001932645,0.00002933728,0.00052028],"genre_scores_gemma":[0.9969536,0.0005196072,0.001086508,0.00002183676,0.00000545589,0.00002526614,0.0007669373,0.000008194143,0.0006126283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000561551,"threshold_uncertainty_score":0.001878619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555489115700087,"score_gpt":0.2045234614779081,"score_spread":0.1889685703209072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}