{"id":"W2112910994","doi":"10.1124/mol.106.028878","title":"[d-Trp8]-γ-Melanocyte-Stimulating Hormone Exhibits Anti-Inflammatory Efficacy in Mice Bearing a Nonfunctional MC1R (Recessive Yellow e/e Mouse)","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Université de Sherbrooke","keywords":"Melanocortins; Melanocortin; Melanocortin 1 receptor; Agonist; Molecular biology; Internal medicine; Endocrinology; Receptor; Antagonist; Melanocortin receptor; Melanocyte-stimulating hormone; Chemistry; Stereochemistry; Biology; Biochemistry; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002448003,0.0002759851,0.0002540792,0.0001605059,0.0001214322,0.0000274516,0.0002091165,0.0002519323,0.00007683668],"category_scores_gemma":[0.00003469702,0.0003139431,0.0001207723,0.000177008,0.00009052742,0.00001164634,0.0001402519,0.0002321457,0.00004536698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006660748,"about_ca_system_score_gemma":0.00008950137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006840943,"about_ca_topic_score_gemma":0.00002768155,"domain_scores_codex":[0.9980803,0.0002096295,0.0004441183,0.0005822581,0.0002147282,0.0004690135],"domain_scores_gemma":[0.9994403,0.00004003311,0.0001688115,0.0001759639,0.00008566637,0.00008923267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001649521,0.0002115432,0.002560918,0.00001839383,0.00006964424,0.0001470234,0.00004407728,0.02045916,0.9735507,0.00005165759,0.002392743,0.0003291855],"study_design_scores_gemma":[0.00379177,0.0001952711,0.009727902,0.00001120614,0.00005039301,0.000038659,0.00003153807,0.002236696,0.9807991,0.00002579921,0.002732986,0.0003586423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933279,0.0009027737,0.003256608,0.0001243631,0.0003682039,0.0004001018,0.00001175884,0.00003674683,0.001571527],"genre_scores_gemma":[0.9970753,0.00006132061,0.0007885279,0.0005102092,0.0004511698,0.00006289517,0.0004125802,0.00005147139,0.000586494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01822246,"threshold_uncertainty_score":0.9999313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007223667164242507,"score_gpt":0.261471855448032,"score_spread":0.2542481882837895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}