{"id":"W2112912180","doi":"10.1093/jnci/djn460","title":"Phase 3 Randomized Trial on Larynx Preservation Comparing Sequential vs Alternating Chemotherapy and Radiotherapy","year":2009,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":282,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre d'expertise et de recherche en infrastructures urbaines","funders":"National Cancer Institute","keywords":"Laryngectomy; Larynx; Radiation therapy; Medicine; Chemotherapy; Randomized controlled trial; Induction chemotherapy; Cancer; Oncology; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003482565,0.001623506,0.003262094,0.000577845,0.0004956782,0.000849036,0.001068664,0.001849673,0.0138133],"category_scores_gemma":[0.003575016,0.0005960452,0.002408869,0.0005792986,0.001298386,0.0009162255,0.0005695777,0.002927323,0.001118938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008760744,"about_ca_system_score_gemma":0.001903224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008542084,"about_ca_topic_score_gemma":0.001466597,"domain_scores_codex":[0.9983103,0.001210874,0.00008457669,0.0001855586,0.00008078989,0.0001277853],"domain_scores_gemma":[0.9973062,0.001198277,0.0006014685,0.0002452981,0.0001327054,0.000516077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9920794,0.002310395,0.0002036545,0.0001619997,0.0002949264,0.00001047995,0.00001054622,0.0002044656,0.0004381991,0.00005841262,0.0002923791,0.003935211],"study_design_scores_gemma":[0.969236,0.02937445,0.0003968063,0.00001960957,0.0001822425,0.00001241581,0.000004443865,0.0002939348,0.0001247869,0.0001291924,0.0002204146,0.000005799707],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771413,0.003486308,0.001590448,0.001018974,0.001073827,0.01107779,0.001550536,0.0001762318,0.002884644],"genre_scores_gemma":[0.9624099,0.001781186,0.004410921,0.002208961,0.0009088952,0.02279485,0.001759488,0.00003846587,0.003687341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0138133,"threshold_uncertainty_score":0.04621005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09673170283128098,"score_gpt":0.4187228316456326,"score_spread":0.3219911288143516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}