{"id":"W2112950614","doi":"10.1016/s0969-2126(00)00143-x","title":"A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins","year":2000,"lang":"en","type":"article","venue":"Structure","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":206,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Medical Research Council; Medical Research Council Canada; Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst; North Atlantic Treaty Organization","keywords":"Lipopolysaccharide; Bacterial outer membrane; Lipid A; Innate immune system; Chemistry; Escherichia coli; Cell biology; Biochemistry; Plasma protein binding; Protein structure; Biophysics; Biology; Receptor; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001928953,0.0004528743,0.0005947293,0.0002528929,0.0005132896,0.0004355947,0.0004439107,0.0004444227,0.0008398647],"category_scores_gemma":[0.0003768586,0.0001874202,0.0004578526,0.000290069,0.0003145975,0.0004510979,0.0004254936,0.0006907531,0.0006988961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003851106,"about_ca_system_score_gemma":0.000351041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003418928,"about_ca_topic_score_gemma":0.0004366298,"domain_scores_codex":[0.9998696,0.00002215321,0.00001385613,0.00003088289,0.0000380985,0.00002540043],"domain_scores_gemma":[0.9996339,0.00004392836,0.0001038904,0.00004582596,0.00005351807,0.0001188947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004473468,0.00002722501,0.0005022513,0.00009536024,0.00001343333,0.0003919887,0.00005123667,0.0001606766,0.9925889,0.001087241,0.0001203439,0.004513826],"study_design_scores_gemma":[0.00007947208,0.001120343,0.02815442,0.00005603784,0.00006745275,0.005480239,0.000163203,0.00288558,0.9491467,0.001112136,0.01167488,0.00005955421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745811,0.002832242,0.02039087,0.0001263303,0.0001105245,0.00006542864,0.00029454,0.0001911047,0.001407886],"genre_scores_gemma":[0.9782912,0.0008168904,0.01742303,0.0001544621,0.00006208683,0.00004930245,0.0009463591,0.00003459118,0.002222277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008398647,"threshold_uncertainty_score":0.002809584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006906108697215097,"score_gpt":0.2113306729065049,"score_spread":0.2044245642092898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}