{"id":"W2112990569","doi":"10.1186/s13075-015-0557-x","title":"Comparison of two hyaluronic acid formulations for safety and efficacy (CHASE) study in knee osteoarthritis: a multicenter, randomized, double-blind, 26-week non-inferiority trial comparing Durolane to Artz","year":2015,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, Shanghai Jiao Tong University; Beijing Friendship Hospital, Capital Medical University; Peking University; Peking University Third Hospital; Shanghai Jiao Tong University; Zhejiang University; Capital Medical University","keywords":"Viscosupplementation; Medicine; Osteoarthritis; WOMAC; Randomized controlled trial; Adverse effect; Hyaluronic acid; Rheumatology; Knee pain; Physical therapy; Clinical trial; Surgery; Internal medicine; Intra articular","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003922378,0.0003849224,0.001951198,0.0007056812,0.0003048852,0.0001250593,0.0002009301,0.0001392443,0.00003091116],"category_scores_gemma":[0.0004513556,0.0003586544,0.0002466692,0.0005853924,0.0002548425,0.0002827205,0.0001601965,0.0005451995,0.00003823672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001791666,"about_ca_system_score_gemma":0.0003432815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005489981,"about_ca_topic_score_gemma":0.00596322,"domain_scores_codex":[0.995317,0.0006595938,0.001327348,0.000714549,0.001041271,0.0009402804],"domain_scores_gemma":[0.9970634,0.0008531533,0.0001833437,0.0006174099,0.0006408524,0.0006418352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8334783,0.005587881,0.00874795,0.00002504537,0.0001357897,0.00004867361,0.006253309,0.00003365374,0.002213838,0.0002567665,0.00002270829,0.143196],"study_design_scores_gemma":[0.9378257,0.05396583,0.0008407913,0.0004258962,0.00005311259,0.00001793388,0.001833937,0.000899423,0.002751242,0.0002348357,0.0008735242,0.0002778127],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662531,0.004577504,0.0004502803,0.0003120566,0.0002948048,0.02771603,0.00003597211,0.00007962056,0.0002806347],"genre_scores_gemma":[0.9950451,0.0004730149,0.001450512,0.00004105332,0.0002427088,0.002473912,0.0001049156,0.00007948469,0.00008935174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1429182,"threshold_uncertainty_score":0.9998866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1636334689170874,"score_gpt":0.4420987399123047,"score_spread":0.2784652709952172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}