{"id":"W2113030300","doi":"10.1155/2012/346053","title":"Induced Pluripotent Stem Cells to Model and Treat Neurogenetic Disorders","year":2012,"lang":"en","type":"review","venue":"Neural Plasticity","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; McMaster University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Induced pluripotent stem cell; Reprogramming; Neuroscience; Somatic cell; Stem cell; Human Induced Pluripotent Stem Cells; Medicine; Embryonic stem cell; Biology; Cell; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001001638,0.0006663864,0.0009235297,0.0001586034,0.0001250697,0.00006863661,0.0004806725,0.0004854494,0.000009167808],"category_scores_gemma":[0.0000299404,0.0005581488,0.0003085325,0.000182314,0.00007726544,0.000006202978,0.0007285976,0.0004259726,0.00008851145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004682763,"about_ca_system_score_gemma":0.0001369585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001920894,"about_ca_topic_score_gemma":0.00004331735,"domain_scores_codex":[0.997146,0.0002333707,0.0004731151,0.0009737746,0.0003649719,0.00080873],"domain_scores_gemma":[0.9986324,0.0000776446,0.000150977,0.0004897382,0.00005045552,0.0005987952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008969144,0.0002134183,0.00002420904,0.006622086,0.0001636757,0.0000159912,0.00002455005,0.001751696,0.05413379,0.000005643333,0.0008949745,0.9360602],"study_design_scores_gemma":[0.0009057634,0.001383132,0.00005430794,0.001077468,0.001499654,0.0001467866,0.0000153266,0.00512002,0.01192006,0.000008126653,0.9756177,0.002251678],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09124818,0.9062803,0.0002425283,0.00002918905,0.0002787657,0.001508611,0.000213055,0.0000313251,0.0001679948],"genre_scores_gemma":[0.04133217,0.9570826,0.00007767439,0.00008240928,0.0002278037,0.0001405485,0.00007037038,0.000126214,0.0008602311],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9747227,"threshold_uncertainty_score":0.999687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06164248454784764,"score_gpt":0.306219581932224,"score_spread":0.2445770973843764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}