{"id":"W2113030300","doi":"10.1155/2012/346053","title":"Induced Pluripotent Stem Cells to Model and Treat Neurogenetic Disorders","year":2012,"lang":"en","type":"review","venue":"Neural Plasticity","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; McMaster University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Induced pluripotent stem cell; Reprogramming; Neuroscience; Somatic cell; Stem cell; Human Induced Pluripotent Stem Cells; Medicine; Embryonic stem cell; Biology; Cell; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007199641,0.00109924,0.0009883865,0.001820615,0.0002731692,0.0006312479,0.0008154425,0.0009424225,0.00434555],"category_scores_gemma":[0.0003539688,0.000282108,0.0004031401,0.001585807,0.000521981,0.000950855,0.0006621163,0.001920235,0.003668444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004937266,"about_ca_system_score_gemma":0.0006995021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006103506,"about_ca_topic_score_gemma":0.0009232699,"domain_scores_codex":[0.9997906,0.00003465876,0.00002452294,0.000027951,0.0001060809,0.00001612878],"domain_scores_gemma":[0.9998492,0.00005200948,0.00002232523,0.000009865576,0.00004954343,0.00001705068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004373213,0.00009249248,0.0001245138,0.008152918,0.00006649036,0.0003918438,0.00006928503,0.0005015314,0.008421625,0.01146659,0.036799,0.9338699],"study_design_scores_gemma":[0.00001352052,0.00004077965,0.000230989,0.0009233704,0.00004301003,0.0008926359,0.00002203912,0.0000712098,0.00183679,0.002556419,0.9933589,0.00001029151],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002257215,0.9927862,0.001197072,0.0004044092,0.000454851,0.00003102353,0.00004198336,0.0000273168,0.004831315],"genre_scores_gemma":[0.001275075,0.994307,0.001041932,0.0003114711,0.0002001161,0.00002683416,0.00007121078,0.000005109491,0.002761358],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00434555,"threshold_uncertainty_score":0.01453727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06164248454784764,"score_gpt":0.306219581932224,"score_spread":0.2445770973843764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}