{"id":"W2113035989","doi":"10.1056/nejmoa065644","title":"Eprodisate for the Treatment of Renal Disease in AA Amyloidosis","year":2007,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":273,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"U.S. Food and Drug Administration","keywords":"Amyloidosis; Amyloid (mycology); Fibril; AA amyloidosis; Medicine; Amyloid fibril; Glycosaminoglycan; Serum amyloid A; Serum Amyloid A Protein; Pathology; Biochemistry; Disease; Chemistry; Immunology; Amyloid β; Inflammation; Anatomy; Familial Mediterranean fever","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001804027,0.0003399434,0.001068443,0.0002629727,0.0001946197,0.0003175802,0.0003177489,0.0006190718,0.001808579],"category_scores_gemma":[0.001493773,0.0001257743,0.0007630661,0.0002672531,0.0004520044,0.0002587218,0.0001946742,0.001284117,0.0001741424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001777985,"about_ca_system_score_gemma":0.0003445701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001471047,"about_ca_topic_score_gemma":0.0002500878,"domain_scores_codex":[0.9995539,0.0002758972,0.00004969084,0.00004902474,0.00004321347,0.0000282015],"domain_scores_gemma":[0.998758,0.0006131249,0.0003765746,0.00005616743,0.00005654148,0.0001396513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4204658,0.01328458,0.01525522,0.005684159,0.002889217,0.0008644016,0.0002198898,0.001761622,0.03555753,0.0009016515,0.002938011,0.5001779],"study_design_scores_gemma":[0.6573772,0.2676563,0.04698015,0.0006505611,0.002084289,0.002314374,0.00007340051,0.001322786,0.007778912,0.0006882007,0.01302814,0.0000456829],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9292884,0.06503414,0.001315029,0.001199684,0.0003604816,0.0009211376,0.0001932974,0.00005482524,0.001632865],"genre_scores_gemma":[0.9835217,0.01286612,0.001395876,0.0006882847,0.0004128805,0.0004699113,0.0001631391,0.000005181555,0.0004768543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001808579,"threshold_uncertainty_score":0.009540677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192381010065085,"score_gpt":0.3038529969746026,"score_spread":0.2846148959680941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}