{"id":"W2113071287","doi":"10.1128/jvi.01511-06","title":"Small Interfering RNAs against the TAR RNA Binding Protein, TRBP, a Dicer Cofactor, Inhibit Human Immunodeficiency Virus Type 1 Long Terminal Repeat Expression and Viral Production","year":2007,"lang":"en","type":"article","venue":"Journal of Virology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Dicer; Biology; Small interfering RNA; RNA silencing; RNA interference; Viral replication; Gene silencing; Molecular biology; RNA; Drosha; Context (archaeology); Virology; Cell biology; Virus; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003521939,0.0006024136,0.0005453367,0.0002707503,0.0001798986,0.0003369102,0.0003570573,0.0003808184,0.00114037],"category_scores_gemma":[0.0002179362,0.0002473849,0.000415068,0.0001519104,0.0002507781,0.0001820685,0.0001934397,0.0006052526,0.0005455184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002792631,"about_ca_system_score_gemma":0.0002302038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002414295,"about_ca_topic_score_gemma":0.0005365612,"domain_scores_codex":[0.9996291,0.00006181673,0.00004974883,0.00007469572,0.0001326133,0.00005198118],"domain_scores_gemma":[0.9998091,0.00006432072,0.00005113683,0.00002195652,0.00002917295,0.00002428349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002250123,0.00001231788,0.00004731838,0.00004684768,0.000006047829,0.00002084483,0.000005104384,0.00003496707,0.9986647,0.0000598758,0.0000357709,0.001043627],"study_design_scores_gemma":[0.00001176084,0.0002055706,0.0007815287,0.000004093316,0.00001625977,0.000126512,0.000005968306,0.0004993207,0.9962549,0.00002427935,0.002066783,0.0000030297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9327365,0.01420303,0.04245849,0.0002669778,0.0002023634,0.0003444479,0.001563226,0.0007400577,0.007485036],"genre_scores_gemma":[0.9544985,0.004934717,0.03046557,0.0002136526,0.00003989146,0.0003246339,0.001988371,0.00007156406,0.00746319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00114037,"threshold_uncertainty_score":0.003814876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01931647559631086,"score_gpt":0.2629506801095899,"score_spread":0.243634204513279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}