{"id":"W2113087532","doi":"10.1074/mcp.m500166-mcp200","title":"Identification of Candidate Regulators of Embryonic Stem Cell Differentiation by Comparative Phosphoprotein Affinity Profiling","year":2005,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ontario Genomics; Institute for Biological Sciences; Ottawa Hospital","funders":"","keywords":"Embryonic stem cell; Biology; Stem cell; Cellular differentiation; Cell biology; Homeobox protein NANOG; Population; Molecular biology; Genetics; Induced pluripotent stem cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002372049,0.0004687186,0.000430972,0.0009274671,0.000237962,0.0004534111,0.0002459182,0.0002265912,0.001068526],"category_scores_gemma":[0.0002816522,0.0001674072,0.0002915798,0.0006736728,0.0002166213,0.0002515345,0.0001938709,0.0002982327,0.0005309993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002850567,"about_ca_system_score_gemma":0.0002723057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005179328,"about_ca_topic_score_gemma":0.0008065761,"domain_scores_codex":[0.9998407,0.00001419049,0.00001211104,0.00005313867,0.00005257656,0.00002723849],"domain_scores_gemma":[0.9997948,0.00004901748,0.00005755969,0.00001324949,0.00004539126,0.00003998859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005845386,0.000008090304,0.0008131932,0.00003689942,0.000005863601,0.00004632534,0.0000137224,0.00003747814,0.9977412,0.00006444856,0.0000335329,0.001140927],"study_design_scores_gemma":[0.00001447972,0.0002323726,0.1182289,0.00001137828,0.00008701109,0.0007091808,0.00009054135,0.002313097,0.8740408,0.0002082504,0.004049843,0.0000142166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812185,0.002884752,0.01099235,0.0000929887,0.00002232542,0.00006014197,0.00285266,0.000158414,0.001717791],"genre_scores_gemma":[0.9695898,0.002298137,0.01756782,0.0001515221,0.00002336568,0.0001347378,0.00754709,0.00006535792,0.002622141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001068526,"threshold_uncertainty_score":0.00357461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008950975978341194,"score_gpt":0.2381401738140509,"score_spread":0.2291891978357098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}