{"id":"W2113123481","doi":"10.1002/jms.1605","title":"The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide‐oligonucleotide adducts determined using nanoLC/MS/MS","year":2009,"lang":"en","type":"article","venue":"Journal of Mass Spectrometry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Cancer Institute; National Institutes of Health","keywords":"Chemistry; Oligonucleotide; Benzo(a)pyrene; CpG site; Epoxide; Adduct; Pyrene; Diol; DNA; Stereochemistry; Methylation; Carcinogen; DNA methylation; Biochemistry; Molecular biology; Gene; Gene expression; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003048978,0.0003393696,0.0002185011,0.0002122908,0.0001743002,0.000227141,0.0002256671,0.0003970454,0.001334982],"category_scores_gemma":[0.0004758808,0.0002225377,0.0001391147,0.0001351013,0.0002516996,0.0001870756,0.0001597696,0.0003334148,0.000379863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002862631,"about_ca_system_score_gemma":0.0002857818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001269305,"about_ca_topic_score_gemma":0.001918909,"domain_scores_codex":[0.9997545,0.00002741697,0.00001275936,0.00009023839,0.0000766411,0.00003848505],"domain_scores_gemma":[0.9997507,0.00009737649,0.00004286885,0.00001137329,0.00005875397,0.00003888007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003008006,0.000004255354,0.0000688772,0.00001042218,0.000002681285,0.000008642494,0.00001004106,0.00001935606,0.9995079,0.000007011204,0.000005158218,0.0003255122],"study_design_scores_gemma":[0.000002647419,0.00006342969,0.001186778,0.000001602571,0.000005351117,0.00003150544,0.000007563533,0.0003853268,0.9980863,0.000006630587,0.0002193825,0.000003433401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934751,0.0007220288,0.004107541,0.00004577742,0.00001945062,0.00004129785,0.0003024075,0.00009716817,0.001189252],"genre_scores_gemma":[0.987914,0.0009097631,0.007947883,0.0001311962,0.000009574801,0.00009292051,0.000385332,0.000050115,0.002559203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001334982,"threshold_uncertainty_score":0.004465997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01197816174030323,"score_gpt":0.2615265091363286,"score_spread":0.2495483473960254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}