{"id":"W2113123481","doi":"10.1002/jms.1605","title":"The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide‐oligonucleotide adducts determined using nanoLC/MS/MS","year":2009,"lang":"en","type":"article","venue":"Journal of Mass Spectrometry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Cancer Institute; National Institutes of Health","keywords":"Chemistry; Oligonucleotide; Benzo(a)pyrene; CpG site; Epoxide; Adduct; Pyrene; Diol; DNA; Stereochemistry; Methylation; Carcinogen; DNA methylation; Biochemistry; Molecular biology; Gene; Gene expression; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001114696,0.0001613388,0.000287756,0.0001334931,0.000112973,0.00002335223,0.0003009488,0.0001156924,0.000007120921],"category_scores_gemma":[0.0009017009,0.0001018574,0.0001861869,0.000353235,0.00009164056,0.00001701635,0.00003242376,0.0002077531,3.401397e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005501611,"about_ca_system_score_gemma":0.0001061545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001228041,"about_ca_topic_score_gemma":0.000009953186,"domain_scores_codex":[0.9984645,0.0001651566,0.0006224996,0.0001590831,0.0003775493,0.000211166],"domain_scores_gemma":[0.9979498,0.0001902119,0.001055511,0.0003496268,0.0003979615,0.00005692485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001911343,0.00007589492,0.002184979,0.000007106463,0.00007119845,0.000001725637,0.00002368633,0.002481761,0.9918472,0.0001411951,0.000009687339,0.002964403],"study_design_scores_gemma":[0.0003192836,0.00117826,0.1194375,0.00004093052,0.00004728628,0.00001288575,0.00001715913,0.0001393899,0.8772095,0.001407109,0.00009875428,0.00009190809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955946,0.001472524,0.002172341,0.0003315951,0.0000844592,0.0001247366,0.00000461949,0.000003013018,0.0002121459],"genre_scores_gemma":[0.9961981,0.0006603468,0.002844871,0.00004431998,0.00021723,6.373677e-7,0.000001299708,0.00001905428,0.00001413725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1172526,"threshold_uncertainty_score":0.4153626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01197816174030323,"score_gpt":0.2615265091363286,"score_spread":0.2495483473960254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}