{"id":"W2113180481","doi":"10.1677/joe-09-0160","title":"Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 β-cell insulin secretion and signal transduction","year":2009,"lang":"en","type":"article","venue":"Journal of Endocrinology","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre","funders":"Health Research Board","keywords":"Internal medicine; Endocrinology; Insulin; Insulin receptor substrate; Insulin receptor; Receptor; Insulin resistance; Biology; Agonist; TLR2; TLR4; Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000291392,0.0005866312,0.0003709939,0.0003598733,0.0001332047,0.0005327536,0.0002528266,0.0002763797,0.003050121],"category_scores_gemma":[0.0002187535,0.0002762285,0.0004633339,0.0003066954,0.0001988971,0.0002371398,0.0002949332,0.001193648,0.001653402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002333807,"about_ca_system_score_gemma":0.000142849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000472098,"about_ca_topic_score_gemma":0.0006090312,"domain_scores_codex":[0.9995852,0.00005268015,0.00005611245,0.0001042073,0.0001222099,0.00007949544],"domain_scores_gemma":[0.999666,0.00006165309,0.00008630323,0.00005560148,0.00004986647,0.00008065347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002208738,0.00005976599,0.0003182148,0.00001790053,0.000004860388,0.00003268875,0.00001664566,0.00001634647,0.9987249,0.00002157172,0.00003389516,0.000532402],"study_design_scores_gemma":[0.00006854662,0.001864201,0.02551058,0.00001452926,0.00004967468,0.0004467159,0.0001220299,0.0005145911,0.968073,0.00003374486,0.003288696,0.00001374241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930634,0.001690472,0.001686871,0.0001027539,0.000068124,0.0000334573,0.001338813,0.00007739347,0.00193871],"genre_scores_gemma":[0.9744522,0.002102989,0.006053324,0.0003005335,0.00004682995,0.0002348744,0.006519117,0.00009834368,0.01019186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003050121,"threshold_uncertainty_score":0.01020366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01808801489827499,"score_gpt":0.2653772601669681,"score_spread":0.2472892452686931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}