{"id":"W2113222090","doi":"10.1128/mcb.00570-08","title":"Acetylation of Rsc4p by Gcn5p Is Essential in the Absence of Histone H3 Acetylation","year":2008,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Acetylation; Biology; Histone octamer; Histone H3; Histone; Histone acetyltransferase; SAP30; HDAC4; Histone H2A; Histone H1; Chromatin; Lysine; Histone code; Chromatin remodeling; Histone methyltransferase; Histone H4; Cell biology; Biochemistry; Nucleosome; Amino acid; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001469582,0.0004842061,0.0003233101,0.0002622063,0.0001954178,0.0003732611,0.0004994884,0.0002770347,0.001011968],"category_scores_gemma":[0.0002935964,0.0002238859,0.0002620299,0.0001910274,0.0005037721,0.0001836938,0.0005006407,0.0003178116,0.0006554773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005872619,"about_ca_system_score_gemma":0.0005340248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00322422,"about_ca_topic_score_gemma":0.003550817,"domain_scores_codex":[0.999714,0.00003810354,0.00002333763,0.00004889867,0.0001227958,0.00005289965],"domain_scores_gemma":[0.9996799,0.00004884266,0.00007680762,0.00006347858,0.00003857167,0.00009233481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009887961,0.000007407559,0.0003525559,0.00001740228,0.000004138831,0.0001390819,0.000005907826,0.0001483774,0.9983075,0.0000860744,0.00003460365,0.0007980957],"study_design_scores_gemma":[0.000008604497,0.000060036,0.005866448,0.000004167082,0.000008622273,0.0002755458,0.00001821602,0.001465354,0.9905196,0.00005168526,0.001715074,0.000006606231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950966,0.0007238656,0.002361772,0.00008879078,0.0000211149,0.00001002625,0.000387369,0.0001333009,0.001177126],"genre_scores_gemma":[0.9963236,0.000226478,0.001124365,0.00002055898,0.000004172583,0.000009218928,0.0006541964,0.00004494959,0.001592466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00322422,"threshold_uncertainty_score":0.006410897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004430373782076101,"score_gpt":0.2311480656125657,"score_spread":0.2267176918304896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}