{"id":"W2113248950","doi":"10.1515/bc.2009.070","title":"Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice","year":2009,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; National Institutes of Health; Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"Epitope; MUC1; Glycopeptide; Genetically modified mouse; Chemistry; Peptide; Transgene; Biochemistry; Biology; Mucin; Immunology; Antigen; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003021539,0.0006062583,0.0004363273,0.0003998553,0.0001454393,0.0003413826,0.0002596116,0.0006169821,0.001088008],"category_scores_gemma":[0.0002608899,0.0002650812,0.0003511707,0.0001460719,0.000331212,0.0003319372,0.0002413925,0.001318679,0.0003668869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002308467,"about_ca_system_score_gemma":0.0002195699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002988766,"about_ca_topic_score_gemma":0.0003169889,"domain_scores_codex":[0.999678,0.00004573324,0.00003129951,0.0000603463,0.00007117526,0.000113388],"domain_scores_gemma":[0.9996054,0.00005539572,0.0001235205,0.00003716405,0.00003047713,0.000147974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002995212,0.0001900152,0.0001952623,0.00002795218,0.000006517371,0.00003524884,0.00001875182,0.00006887213,0.9980837,0.00005161689,0.00003650822,0.0009860337],"study_design_scores_gemma":[0.0002554636,0.005339483,0.008785724,0.00002357749,0.00006034916,0.0006613987,0.0000413524,0.00119343,0.9810662,0.0001208664,0.00243828,0.00001397112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980311,0.0003191439,0.0007357429,0.00008944039,0.0000193044,0.00003235997,0.000156894,0.00009452681,0.0005215029],"genre_scores_gemma":[0.9950699,0.0003432579,0.001170436,0.0001494225,0.00002181584,0.00005507148,0.0004717367,0.00005298744,0.002665399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001088008,"threshold_uncertainty_score":0.003639698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644964248631395,"score_gpt":0.2731177037326786,"score_spread":0.2566680612463646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}