{"id":"W2113248950","doi":"10.1515/bc.2009.070","title":"Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice","year":2009,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; National Institutes of Health; Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"Epitope; MUC1; Glycopeptide; Genetically modified mouse; Chemistry; Peptide; Transgene; Biochemistry; Biology; Mucin; Immunology; Antigen; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005706213,0.0004048218,0.0004592268,0.00007218495,0.0001368953,0.00007749785,0.0004787855,0.0004304963,0.00006805978],"category_scores_gemma":[0.001437141,0.0003533975,0.0001474226,0.0003697863,0.00009235724,0.00001084063,0.0001743705,0.0003470698,0.00003458188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008937988,"about_ca_system_score_gemma":0.0001153433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006759909,"about_ca_topic_score_gemma":0.0001059069,"domain_scores_codex":[0.9972209,0.0001917682,0.0004889186,0.001067313,0.0002641535,0.0007668905],"domain_scores_gemma":[0.9987351,0.00009700486,0.000114393,0.000446509,0.0001715628,0.0004354793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001287676,0.0002417497,0.005864623,0.0000324471,0.00002397348,0.00003458321,0.00006239751,0.0000174255,0.9900413,0.000004541698,0.0006634959,0.001725789],"study_design_scores_gemma":[0.001149128,0.0007590986,0.1262671,0.00006555374,0.000007497602,0.00001993438,0.0001038228,0.00002721554,0.8524625,0.00003577047,0.0185826,0.0005197013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962256,0.0005742672,0.00004204055,0.001482262,0.00005248519,0.00066699,0.0001438488,0.00007617017,0.0007363412],"genre_scores_gemma":[0.9947502,0.0002370101,0.0009646437,0.002190425,0.00026276,0.0001217158,0.00008556255,0.00002425167,0.001363411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1375788,"threshold_uncertainty_score":0.9998918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644964248631395,"score_gpt":0.2731177037326786,"score_spread":0.2566680612463646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}