{"id":"W2113276710","doi":"10.1016/j.febslet.2004.09.083","title":"Expression of Concern: Mitogen‐activated protein kinase phosphatase‐1 (MKP‐1): >100‐fold nocturnal and norepinephrine‐induced changes in the rat pineal gland","year":2004,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta; Faculty of Medicine and Dentistry, University of Alberta; Wellcome Trust","keywords":"Endocrinology; Pineal gland; Protein kinase A; Internal medicine; Phosphatase; Propranolol; MAPK/ERK pathway; Kinase; Norepinephrine; Pinealocyte; Receptor; Biology; Chemistry; Mitogen-activated protein kinase; Phosphorylation; Cell biology; Circadian rhythm; Medicine; Dopamine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001685467,0.0002224446,0.0002384567,0.0001299901,0.0001189708,0.0000545131,0.0002478296,0.00008459627,0.00002769095],"category_scores_gemma":[0.0001405027,0.0001603392,0.00004593754,0.0003675878,0.0001606342,0.0001812557,0.00006374722,0.0002915444,0.000007191675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000480106,"about_ca_system_score_gemma":0.00004461122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001490222,"about_ca_topic_score_gemma":0.0000530515,"domain_scores_codex":[0.9984823,0.0001389049,0.0002497649,0.0004170573,0.0003387477,0.0003732079],"domain_scores_gemma":[0.9992862,0.00009732649,0.0001692504,0.0003244627,0.00001715653,0.0001056372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001608837,0.00004743936,0.0005466253,0.00003373454,0.000002488958,0.0002158131,0.001145364,0.00003313995,0.996493,0.0004060001,0.0004395584,0.0004759966],"study_design_scores_gemma":[0.002514581,0.000116552,0.005263579,0.0001797673,0.000007469615,0.00008517721,0.00006572791,0.00001007806,0.9885446,0.00002136015,0.00300018,0.0001908986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919288,0.0002924266,0.00002332803,0.006675933,0.0002574285,0.0006933305,0.00005449445,0.00002951969,0.00004471691],"genre_scores_gemma":[0.994646,0.00002871368,0.00005876406,0.004945637,0.0001883542,0.00006822295,0.0000135246,0.00002084793,0.00002995195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007948327,"threshold_uncertainty_score":0.6538444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02877008146278904,"score_gpt":0.249541442395661,"score_spread":0.220771360932872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}