{"id":"W2113276710","doi":"10.1016/j.febslet.2004.09.083","title":"Expression of Concern: Mitogen‐activated protein kinase phosphatase‐1 (MKP‐1): >100‐fold nocturnal and norepinephrine‐induced changes in the rat pineal gland","year":2004,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta; Faculty of Medicine and Dentistry, University of Alberta; Wellcome Trust","keywords":"Endocrinology; Pineal gland; Protein kinase A; Internal medicine; Phosphatase; Propranolol; MAPK/ERK pathway; Kinase; Norepinephrine; Pinealocyte; Receptor; Biology; Chemistry; Mitogen-activated protein kinase; Phosphorylation; Cell biology; Circadian rhythm; Medicine; Dopamine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000131972,0.0004360656,0.0002077636,0.0003684718,0.0002325424,0.0003942968,0.0001501758,0.0002936202,0.001939657],"category_scores_gemma":[0.0001222868,0.0001705269,0.0002251064,0.0002065593,0.0002848719,0.0003308948,0.0002022189,0.0006239827,0.0006090297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005311822,"about_ca_system_score_gemma":0.0002637448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006598469,"about_ca_topic_score_gemma":0.0009165053,"domain_scores_codex":[0.9998683,0.000007951495,0.000009052843,0.00003372137,0.00003441042,0.00004649534],"domain_scores_gemma":[0.9998399,0.00001446217,0.00003175032,0.00001433855,0.00001849941,0.00008103391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001244394,0.00002753773,0.0003030667,0.00003176767,0.000004920125,0.00006259081,0.00001208092,0.00001894268,0.9979184,0.0001183553,0.00007503365,0.001302933],"study_design_scores_gemma":[0.0000262315,0.0003804297,0.01921081,0.00001245094,0.00002440535,0.0004300268,0.00005914789,0.0006287535,0.9757106,0.0001476001,0.003362399,0.000007094305],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"editorial","genre_scores_codex":[0.9858096,0.004657254,0.003503342,0.0003720431,0.0001318411,0.00002670171,0.001005481,0.0002716508,0.004222007],"genre_scores_gemma":[0.9818118,0.002224131,0.003251475,0.0001191727,0.00005771217,0.00009068763,0.002176305,0.00005431047,0.01021443],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.9997064,"threshold_uncertainty_score":0.0064888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02877008146278904,"score_gpt":0.249541442395661,"score_spread":0.220771360932872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}