{"id":"W2113347449","doi":"10.1101/cshperspect.a003616","title":"Group II Introns: Mobile Ribozymes that Invade DNA","year":2010,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":478,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Group II intron; Ribozyme; Intron; Biology; RNA splicing; Retrotransposon; Minor spliceosome; Group I catalytic intron; Spliceosome; Genetics; Mobile genetic elements; RNA; Reverse transcriptase; Gene; Computational biology; Genome; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005270608,0.0006632765,0.001340387,0.000281147,0.0001711143,0.00003719386,0.0009109207,0.001564359,0.00009799482],"category_scores_gemma":[0.0002782248,0.0005885803,0.0004976409,0.0001842511,0.0003470017,0.000007151067,0.0006746865,0.0007515727,0.000035855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001331276,"about_ca_system_score_gemma":0.0002010061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003695098,"about_ca_topic_score_gemma":0.00008023863,"domain_scores_codex":[0.9970351,0.0004180043,0.0005018713,0.001292186,0.000104031,0.0006487459],"domain_scores_gemma":[0.9983411,0.0001012356,0.0003556799,0.001026449,0.00005145974,0.0001240445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001051594,0.0007341718,0.0002448139,0.002322842,0.0007354758,0.00004487715,0.0002877285,8.04083e-7,0.5994923,0.1404783,0.0001868582,0.2553667],"study_design_scores_gemma":[0.0002527548,0.0004429269,0.00002486159,0.0008159388,0.0001010943,0.000007088569,0.000083688,4.383658e-7,0.01343381,0.0001493515,0.984019,0.0006690633],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003922065,0.9933789,0.0002199323,0.00002395033,0.0007032061,0.001321954,0.00006388302,0.0000463893,0.0003196552],"genre_scores_gemma":[0.01164705,0.9846327,0.001260925,0.00004161631,0.0008161565,0.001274667,0.00003339248,0.000112599,0.000180934],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9838321,"threshold_uncertainty_score":0.9997318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02547916511866414,"score_gpt":0.3069430699215442,"score_spread":0.28146390480288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}