{"id":"W2113347449","doi":"10.1101/cshperspect.a003616","title":"Group II Introns: Mobile Ribozymes that Invade DNA","year":2010,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":478,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Group II intron; Ribozyme; Intron; Biology; RNA splicing; Retrotransposon; Minor spliceosome; Group I catalytic intron; Spliceosome; Genetics; Mobile genetic elements; RNA; Reverse transcriptase; Gene; Computational biology; Genome; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000324593,0.0008472593,0.0008345795,0.00138349,0.0001966109,0.0009080168,0.0008176733,0.001009929,0.002310418],"category_scores_gemma":[0.0003037804,0.0002850251,0.0003036072,0.001273831,0.0007827329,0.001263457,0.0004170642,0.001431649,0.004252858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006985588,"about_ca_system_score_gemma":0.0006446283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004530349,"about_ca_topic_score_gemma":0.0006088832,"domain_scores_codex":[0.999867,0.00001602193,0.00001382352,0.00003118647,0.00005559988,0.00001643545],"domain_scores_gemma":[0.9998904,0.00003824046,0.00001835462,0.00000651766,0.00002694442,0.0000194509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006820165,0.00005373044,0.0001987603,0.004642833,0.00003755765,0.0002923817,0.00007658523,0.0006236788,0.01378315,0.01821074,0.03421038,0.9278019],"study_design_scores_gemma":[0.00001102214,0.00002989582,0.0001947693,0.0003765738,0.00001466403,0.0007516107,0.00001835255,0.00007690895,0.002027725,0.00270884,0.9937792,0.00001033584],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003329637,0.9917903,0.001316916,0.0002933374,0.0006120999,0.00001130767,0.00002202737,0.00003589108,0.005585083],"genre_scores_gemma":[0.003161562,0.9893909,0.001457557,0.0003986245,0.0003782291,0.00002585764,0.00007991078,0.000007840526,0.005099589],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002310418,"threshold_uncertainty_score":0.007729113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02547916511866414,"score_gpt":0.3069430699215442,"score_spread":0.28146390480288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}