{"id":"W2113415037","doi":"10.1007/3-540-29715-4_11","title":"Mutation-Specific Pharmacology of the Long QT Syndrome","year":2006,"lang":"en","type":"review","venue":"Handbook of experimental pharmacology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Columbia College","funders":"National Heart, Lung, and Blood Institute","keywords":"Long QT syndrome; Disease; Medicine; Short QT syndrome; Mutation; Bioinformatics; Genetics; Neuroscience; QT interval; Internal medicine; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004205816,0.001323677,0.002218891,0.002302382,0.0002366181,0.0007498686,0.001205502,0.001063923,0.003240904],"category_scores_gemma":[0.0005080599,0.0003336005,0.0005935483,0.001799081,0.0006155387,0.00134913,0.0006210891,0.002236308,0.003170962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004714691,"about_ca_system_score_gemma":0.0008510943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006882177,"about_ca_topic_score_gemma":0.001248535,"domain_scores_codex":[0.999845,0.0000264632,0.00002670328,0.0000297494,0.00005851554,0.00001348883],"domain_scores_gemma":[0.9997904,0.0001023781,0.0000274649,0.00001071581,0.00004626134,0.00002294875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001367423,0.000202719,0.000151308,0.0101762,0.00007884476,0.0006086275,0.00003727348,0.0005229767,0.004918813,0.004175222,0.04875289,0.9302384],"study_design_scores_gemma":[0.00007959771,0.0001917496,0.001144542,0.002004936,0.0001245033,0.005581045,0.00003501202,0.0002632351,0.0008828158,0.003808095,0.9858429,0.00004153873],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001467262,0.9970766,0.0005594858,0.0002032341,0.0004402365,0.000008485841,0.00002708961,0.00002127917,0.001516924],"genre_scores_gemma":[0.0006380956,0.996726,0.000695248,0.0003161429,0.0005731198,0.00001136487,0.00005399655,0.000003039945,0.0009829284],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003240904,"threshold_uncertainty_score":0.01084191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02817922706264153,"score_gpt":0.362733672144951,"score_spread":0.3345544450823095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}