{"id":"W2113472021","doi":"10.1081/bio-120028673","title":"Effects of Combined Oral Administration and Intravenous Injection on Maintaining Decreased Systemic Tyrosine Levels in Rats","year":2004,"lang":"en","type":"article","venue":"Artificial Cells Blood Substitutes and Biotechnology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Tyrosinase; Tyrosine; Systemic administration; Oral administration; Medicine; Pharmacology; Systemic reaction; Chemistry; Enzyme; Biochemistry; Biology; Immunology; Allergy; In vivo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001216838,0.000118838,0.0001651011,0.0001074949,0.00005738785,0.00001460116,0.00004849909,0.0002743974,9.370685e-7],"category_scores_gemma":[0.00005151517,0.0001155466,0.00001898647,0.0001118613,0.0001289616,0.00000535315,0.00002648666,0.00008635721,9.480784e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001099587,"about_ca_system_score_gemma":0.00004354596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008469067,"about_ca_topic_score_gemma":0.0002298905,"domain_scores_codex":[0.9992663,0.00003868139,0.0002310026,0.00025682,0.0000580593,0.0001491204],"domain_scores_gemma":[0.9997345,0.0000201466,0.00008659588,0.000101838,0.00002176628,0.00003516016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203269,0.0002054748,0.0004134664,0.00005856922,0.0000194518,0.00002225006,0.00005480995,0.00008355315,0.987262,0.009063391,0.00000126313,0.002595427],"study_design_scores_gemma":[0.001153704,0.002238151,0.001944059,0.00007206918,0.00003031481,0.00005786337,0.0001143561,0.00003902342,0.9929399,0.001289581,0.000007119559,0.0001138587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983335,0.0003028927,0.0007886735,0.000134933,0.0001187865,0.0002880941,0.000005158327,0.00001585993,0.00001216597],"genre_scores_gemma":[0.9992859,0.0001941516,0.0003886223,0.00004741672,0.00002690889,0.00001191302,0.00003304015,0.000007987504,0.000004039627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00777381,"threshold_uncertainty_score":0.4711855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008766637405823176,"score_gpt":0.2273320783180785,"score_spread":0.2185654409122553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}