{"id":"W2113476651","doi":"10.1182/blood-2012-10-457507","title":"The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Queen's University","funders":"National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Von Willebrand factor; Von Willebrand disease; Allele; Molecular biology; Chemistry; Receptor; Lectin; Biology; Internal medicine; Genetics; Endocrinology; Immunology; Platelet; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002957924,0.0003301811,0.0002323603,0.0006251125,0.0002092196,0.0002231498,0.000226233,0.0003533227,0.001651702],"category_scores_gemma":[0.0006734417,0.0001867188,0.0001786639,0.0002285527,0.0002030189,0.00009847994,0.0002090766,0.0002409328,0.0002290007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002890652,"about_ca_system_score_gemma":0.0001107529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001141054,"about_ca_topic_score_gemma":0.0008459448,"domain_scores_codex":[0.99975,0.00008199159,0.00001872057,0.00005765149,0.00006010601,0.00003155864],"domain_scores_gemma":[0.9998131,0.00004538275,0.00007044103,0.00001743248,0.00002097093,0.0000327048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001930539,0.0002368864,0.365141,0.00006893965,0.0002686741,0.001260131,0.0001704389,0.0004032252,0.613444,0.0003567817,0.000747385,0.01597195],"study_design_scores_gemma":[0.00007755295,0.0004680271,0.9539468,0.00002007658,0.000155106,0.005393912,0.00007549722,0.002359914,0.03522693,0.000367018,0.001893398,0.00001566183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992878,0.0001973138,0.0002390844,0.00002300197,0.000003528684,0.000004026261,0.00005699805,0.000006181703,0.0001821446],"genre_scores_gemma":[0.9988384,0.00009210833,0.0004692696,0.00001597376,0.000007097899,0.000005311474,0.000135247,0.000004252596,0.0004323309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001651702,"threshold_uncertainty_score":0.005525529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208933617005748,"score_gpt":0.2382700665043047,"score_spread":0.2261807303342472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}