{"id":"W2113536669","doi":"10.1093/molbev/msq058","title":"Birth-and-Death Long-Term Evolution Promotes Histone H2B Variant Diversification in the Male Germinal Cell Line","year":2010,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Universidade da Coruña; University of Houston","keywords":"Biology; Neofunctionalization; Histone; Subfunctionalization; Chromatin; Evolutionary biology; Histone H2B; Genetics; Histone H1; Lineage (genetic); Histone H2A; Gene duplication; Epigenetics; Histone H4; Histone code; Gene; Genome; Nucleosome; Gene family","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002971532,0.0001392659,0.0001049586,0.00006006763,0.0001394482,0.0000166707,0.0001379288,0.0002800201,0.000006896819],"category_scores_gemma":[0.00003349569,0.00011606,0.00003889542,0.00006512465,0.0001371635,0.000005300252,0.00008933007,0.0001812523,0.000003854193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002355155,"about_ca_system_score_gemma":0.00004075466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006974127,"about_ca_topic_score_gemma":0.0001367994,"domain_scores_codex":[0.9991415,0.00009897342,0.0001669313,0.0003394193,0.00005139528,0.0002017586],"domain_scores_gemma":[0.9995643,0.000009437609,0.00008650903,0.0002560252,0.00004248952,0.00004123289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003892605,0.00008145443,0.09254471,0.00002186415,0.00001021662,0.000008884376,0.00005632765,0.00001026364,0.9023784,0.004355705,0.00001107002,0.0004821864],"study_design_scores_gemma":[0.001100147,0.0006334419,0.9646396,0.00001266375,0.00006524153,0.0004946574,0.00007974206,0.003063122,0.02543287,0.003724923,0.0003774751,0.0003761429],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752033,0.001234946,0.02280009,0.0002450865,0.0001203349,0.0002213563,0.00001777056,0.000006907304,0.0001501975],"genre_scores_gemma":[0.9984331,0.0001294218,0.0009096317,0.00006968364,0.0000778019,0.0000217199,0.0002369012,0.000009623479,0.0001121683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8769455,"threshold_uncertainty_score":0.473279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004857445237831012,"score_gpt":0.2353647354409469,"score_spread":0.2305072902031159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}