{"id":"W2113536669","doi":"10.1093/molbev/msq058","title":"Birth-and-Death Long-Term Evolution Promotes Histone H2B Variant Diversification in the Male Germinal Cell Line","year":2010,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Universidade da Coruña; University of Houston","keywords":"Biology; Neofunctionalization; Histone; Subfunctionalization; Chromatin; Evolutionary biology; Histone H2B; Genetics; Histone H1; Lineage (genetic); Histone H2A; Gene duplication; Epigenetics; Histone H4; Histone code; Gene; Genome; Nucleosome; Gene family","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001421259,0.00008595449,0.0001313356,0.0001781568,0.000143755,0.000290069,0.0001420994,0.0001360484,0.0007664081],"category_scores_gemma":[0.0001498833,0.0001179041,0.0001152135,0.0001380529,0.0001700463,0.0001403339,0.0003775683,0.0002899849,0.0002220492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001996168,"about_ca_system_score_gemma":0.0001040207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003544311,"about_ca_topic_score_gemma":0.0006761911,"domain_scores_codex":[0.9999237,0.00001190951,0.000003941468,0.00001946859,0.00002124393,0.00001976457],"domain_scores_gemma":[0.9998517,0.00002907975,0.00003552147,0.00002309463,0.00001919391,0.00004143279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001099798,0.000009068354,0.007519798,0.00001067643,0.00001056846,0.00008031708,0.00003536829,0.0000819433,0.9895097,0.0001180185,0.0000148099,0.00249976],"study_design_scores_gemma":[0.000024565,0.0004307898,0.5433455,0.000009413838,0.00004342143,0.001253619,0.0002738453,0.002801372,0.4484921,0.0003193975,0.002987969,0.00001808032],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986306,0.0003075162,0.0006606808,0.00001399173,0.000001569983,0.000002007681,0.00003552366,0.000009486939,0.0003387056],"genre_scores_gemma":[0.9988392,0.0001331338,0.0003102685,0.00001732695,0.000002930584,0.000002804226,0.0001502497,0.000007695362,0.0005362771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007664081,"threshold_uncertainty_score":0.002563834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004857445237831012,"score_gpt":0.2353647354409469,"score_spread":0.2305072902031159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}