{"id":"W2113539573","doi":"10.3109/03630269.2013.788511","title":"Mild β+-Thalassemia Associated With Two Linked Sequence Variants: IVS-II-839 (T>C) and IVS-II-844 (C>A)","year":2013,"lang":"en","type":"article","venue":"Hemoglobin","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Hamilton Health Sciences; Hamilton Regional Laboratory Medicine Program","funders":"","keywords":"Polypyrimidine tract; Sequence (biology); Genetics; Allele; Thalassemia; RNA splicing; Biology; Molecular biology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005282224,0.0007880736,0.001074457,0.0002773631,0.0007698365,0.0001322657,0.0003470934,0.0007645373,0.001193415],"category_scores_gemma":[0.0005205579,0.0006193432,0.0002040841,0.001062498,0.0005105516,0.0004732912,0.0003212327,0.001115864,0.0004049682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003967518,"about_ca_system_score_gemma":0.0004460549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007182501,"about_ca_topic_score_gemma":0.00006283295,"domain_scores_codex":[0.9956447,0.0001864987,0.0008383923,0.001119667,0.0008557298,0.001355018],"domain_scores_gemma":[0.9972513,0.0001999897,0.0003265937,0.0009165503,0.0004929668,0.0008125592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.003437757,0.01141484,0.20485,0.002418557,0.008936875,0.005327171,0.03276379,0.003253885,0.258864,0.008260314,0.3880094,0.07246351],"study_design_scores_gemma":[0.1351356,0.02062318,0.3654549,0.01837401,0.006936395,0.00783825,0.01287141,0.2229292,0.01310316,0.006832908,0.1765146,0.01338638],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751232,0.001258202,0.00008182381,0.005868408,0.0002143595,0.001679474,0.00006909032,0.0005073523,0.01519812],"genre_scores_gemma":[0.9844306,0.0005931868,0.001554935,0.002891534,0.0002062469,0.0001377608,0.000224703,0.0001532978,0.009807731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2457608,"threshold_uncertainty_score":0.9997196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01422792179526174,"score_gpt":0.2426597324359316,"score_spread":0.2284318106406699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}