{"id":"W2113580630","doi":"10.1034/j.1399-5618.2003.00019.x","title":"Bipolar depression: criteria for treatment selection, definition of refractoriness, and treatment options","year":2003,"lang":"en","type":"review","venue":"Bipolar Disorders","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of British Columbia","funders":"","keywords":"Bipolar disorder; Lamotrigine; Depression (economics); Lithium (medication); Mood stabilizer; Antidepressant; Refractory period; Psychiatry; Bupropion; Mood; Psychology; Refractory (planetary science); Medicine; Internal medicine; Anxiety; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03779588,0.002119639,0.008330628,0.006179373,0.001316096,0.003680774,0.003013615,0.002829151,0.004459537],"category_scores_gemma":[0.05720171,0.0007759398,0.003539258,0.006065773,0.002028933,0.002816588,0.002359236,0.003809127,0.001656806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005003082,"about_ca_system_score_gemma":0.01261325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003746565,"about_ca_topic_score_gemma":0.007047316,"domain_scores_codex":[0.9607459,0.02061561,0.01173343,0.0007221805,0.005777675,0.0004051728],"domain_scores_gemma":[0.9675707,0.01789515,0.006542217,0.0009146514,0.006361024,0.0007162007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004941738,0.0001143794,0.00199811,0.08206956,0.0006972565,0.0004006064,0.0008300876,0.0004416311,0.0006326587,0.01244312,0.08039593,0.8194825],"study_design_scores_gemma":[0.001617666,0.0005591516,0.009959332,0.3572302,0.003050206,0.004607296,0.00151177,0.001259733,0.0004784728,0.0247958,0.5947083,0.0002220094],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00064948,0.9681015,0.005513948,0.01388795,0.002832219,0.003771567,0.0003974983,0.00006511901,0.004780786],"genre_scores_gemma":[0.02131373,0.8577221,0.08357951,0.01578183,0.004453503,0.01180689,0.001941289,0.00008847616,0.003312602],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03779588,"threshold_uncertainty_score":0.1998861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06875488830240745,"score_gpt":0.3546458008268467,"score_spread":0.2858909125244392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}