{"id":"W2113588550","doi":"10.1111/j.1582-4934.2009.00930.x","title":"Transport characteristics of a novel peptide platform for CNS therapeutics","year":2009,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; Université de Montréal; Angiochem (Canada); Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glial fibrillary acidic protein; Blood–brain barrier; Peptide; Receptor; Astrocyte; Cell biology; Biology; Chemistry; Cancer research; Immunohistochemistry; Neuroscience; Central nervous system; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002573145,0.0001293594,0.0003096912,0.00007224685,0.00002311295,0.00000346271,0.0001310094,0.0001016365,0.000004918195],"category_scores_gemma":[0.00003389065,0.00009776206,0.0001436348,0.00004213026,0.00007667222,0.000005126139,0.000007752864,0.00008900314,9.081824e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004426128,"about_ca_system_score_gemma":0.00005661116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001819126,"about_ca_topic_score_gemma":6.944061e-7,"domain_scores_codex":[0.9991162,0.000008418272,0.0004613465,0.0001129849,0.0001632569,0.0001377314],"domain_scores_gemma":[0.9992096,0.000009682268,0.0002914371,0.0001385051,0.000266384,0.00008436338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003222801,0.00009203456,0.0001233042,0.00002906334,0.0001098628,0.00001723317,0.0001348814,0.000004497789,0.9931952,0.0001321064,0.0001272487,0.005712252],"study_design_scores_gemma":[0.002800288,0.005475204,0.00268422,0.0001674682,0.0003062852,0.0001582127,0.0001804078,0.00007990993,0.9687381,0.0002223569,0.01902337,0.0001641748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8444351,0.002466524,0.1522278,0.0004427101,0.0001167447,0.0000985326,0.0000108098,0.000001269732,0.0002004963],"genre_scores_gemma":[0.9964104,0.0009329178,0.001251492,0.0009889337,0.0002616856,8.891091e-7,0.00003836551,0.00001108589,0.0001042449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1519753,"threshold_uncertainty_score":0.3986621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01927607546561073,"score_gpt":0.2644778495096313,"score_spread":0.2452017740440205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}