{"id":"W2113610600","doi":"10.1164/rccm.200807-1020oc","title":"Deleterious Role of TLR3 during Hyperoxia-induced Acute Lung Injury","year":2008,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"ARDS; Hyperoxia; Medicine; Inflammation; Lung; Immunology; TLR3; Diffuse alveolar damage; Cancer research; Innate immune system; Immune system; Internal medicine; Toll-like receptor; Acute respiratory distress","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002934388,0.0004159041,0.0002360158,0.0002409677,0.0001979168,0.0003232814,0.0002451181,0.0005840108,0.001844478],"category_scores_gemma":[0.0002118072,0.0001081283,0.0004137474,0.0001300715,0.0002973078,0.0002396334,0.0003232651,0.0006929144,0.0004944927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000276608,"about_ca_system_score_gemma":0.0002022094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002242102,"about_ca_topic_score_gemma":0.0003110773,"domain_scores_codex":[0.9998063,0.0000428129,0.00002374689,0.00002771999,0.00004237428,0.00005700767],"domain_scores_gemma":[0.9998198,0.00001961148,0.00008098129,0.00001799281,0.00002369409,0.0000379878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001007495,0.00004848223,0.002112554,0.0001093159,0.00001236552,0.0002966325,0.00001752168,0.00006465799,0.9948764,0.00007054204,0.0000664775,0.00131761],"study_design_scores_gemma":[0.00009455662,0.001993222,0.06020564,0.00006218681,0.00008493641,0.004954226,0.0001567745,0.001351779,0.9286616,0.0002829756,0.002136022,0.00001611234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937908,0.002393227,0.002326748,0.0002382998,0.00004657083,0.00004221955,0.0003558163,0.00006670753,0.0007396351],"genre_scores_gemma":[0.9969833,0.0007668559,0.001020385,0.0001273552,0.00001974333,0.00005725427,0.0003741424,0.000007901281,0.0006429608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001844478,"threshold_uncertainty_score":0.006170332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008993775564822594,"score_gpt":0.2724960074190824,"score_spread":0.2635022318542597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}