{"id":"W2113929252","doi":"10.1172/jci15336","title":"A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes","year":2002,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Elizabeth Glaser Pediatric AIDS Foundation","keywords":"Cell biology; Chemokine; Transcription factor; Biology; T cell; Proinflammatory cytokine; EIF4E; p38 mitogen-activated protein kinases; Effector; MAPK/ERK pathway; Kinase; Inflammation; Translation (biology); Immunology; Immune system; Gene; Messenger RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001038229,0.00009734277,0.0003194397,0.0001655481,0.00007031773,0.00001549657,0.00009249054,0.0002384667,0.0007497999],"category_scores_gemma":[0.001300246,0.0000777013,0.0002308172,0.0001009869,0.0001357517,0.0003878272,0.000007158399,0.0003103761,0.00006092022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002664672,"about_ca_system_score_gemma":0.00004924227,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003302712,"about_ca_topic_score_gemma":0.000002584227,"domain_scores_codex":[0.9980433,0.0002840506,0.001361084,0.0001255556,0.00005529232,0.0001307171],"domain_scores_gemma":[0.9977774,0.001210501,0.0006828956,0.00008164064,0.0002172716,0.00003026979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002580328,0.0005251477,0.03839218,0.00005081114,0.000156158,0.00000389967,0.001318082,0.0004188574,0.8391668,0.0007202418,0.08071743,0.03595003],"study_design_scores_gemma":[0.02351845,0.002208786,0.1111164,0.001045085,0.0001425256,0.0002772143,0.0005508168,0.006735148,0.62577,0.01131506,0.2168441,0.0004764039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873446,0.002953643,0.002556007,0.002366924,0.004281414,0.0002027223,0.000002747422,0.00001669635,0.000275239],"genre_scores_gemma":[0.994531,0.0003712371,0.001936133,0.0004383039,0.0001926207,0.000006106994,0.00003444585,0.00001095381,0.002479244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2133968,"threshold_uncertainty_score":0.8209783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07463683282965859,"score_gpt":0.3324770744528582,"score_spread":0.2578402416231996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}