{"id":"W2113936882","doi":"10.1006/bbrc.2002.6607","title":"Metformin Effects on Dipeptidylpeptidase IV Degradation of Glucagon-like Peptide-1","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Metformin; Glucagon-like peptide-1; Surface plasmon resonance; Chemistry; Dipeptidyl peptidase; Dipeptidyl peptidase-4; Internal medicine; Endocrinology; Hydrolysis; Peptide; Vildagliptin; Glycemic; Enzyme; Pharmacology; Biochemistry; Diabetes mellitus; Type 2 diabetes; Medicine; Nanoparticle; Nanotechnology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002349345,0.000130358,0.0002397713,0.0001579845,0.0001573286,0.0000233326,0.0002882496,0.0000723964,0.00003863241],"category_scores_gemma":[0.000309298,0.00009682954,0.0001005586,0.0004638765,0.0004997362,0.00006325533,0.000305145,0.0002991608,0.0001191022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006185465,"about_ca_system_score_gemma":0.00001449585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002878422,"about_ca_topic_score_gemma":0.00000138435,"domain_scores_codex":[0.9986899,0.0001133821,0.0002019303,0.0002400268,0.0004681632,0.0002865619],"domain_scores_gemma":[0.9977961,0.0007893325,0.0000423678,0.0009893851,0.0001661641,0.0002166123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001247452,0.003494192,0.0003934062,0.0003269447,0.0001852327,0.000005977758,0.0001179991,5.307983e-8,0.8395042,0.01497873,0.02047873,0.1203898],"study_design_scores_gemma":[0.003313838,0.003430307,0.008285047,0.00087454,0.0002983891,0.000004537254,0.0002080129,0.003429937,0.9262207,0.001578115,0.05198101,0.0003755229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828663,0.0009936321,0.00001158116,0.004233756,0.00001581821,0.0006509155,0.00001142059,0.00004190191,0.01117465],"genre_scores_gemma":[0.9927238,0.00151026,0.001679271,0.0001300749,0.00005086434,0.0001286936,0.0001057669,0.00001267106,0.003658557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1200142,"threshold_uncertainty_score":0.3948594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08153660429434237,"score_gpt":0.3536752917050506,"score_spread":0.2721386874107082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}