{"id":"W2113973956","doi":"10.1093/intimm/dxh254","title":"Immunosynapse formation coincides with rapid activation of NK cells by syngeneic T cells and correlates with clustering of MHC class I","year":2005,"lang":"en","type":"article","venue":"International Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"MHC restriction; Interleukin 21; CD1; Cell biology; Antigen-presenting cell; MHC class I; Ionomycin; Cytotoxic T cell; T cell; Major histocompatibility complex; ZAP70; Chemistry; Janus kinase 3; Interleukin 12; MHC class II; IL-2 receptor; Biology; Molecular biology; Antigen; CD8; Immunology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001076088,0.0003116992,0.0003349945,0.0001863123,0.0001651868,0.0004065766,0.0001760987,0.0002764058,0.001513533],"category_scores_gemma":[0.0001409321,0.000208658,0.0002808925,0.0001321154,0.0002058472,0.0002501584,0.0003375275,0.000838867,0.0007857592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003463832,"about_ca_system_score_gemma":0.0001346317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002313363,"about_ca_topic_score_gemma":0.0003795991,"domain_scores_codex":[0.9997458,0.00003470093,0.00001964493,0.00007273282,0.00005647857,0.00007062886],"domain_scores_gemma":[0.9997835,0.00003427629,0.00006209968,0.00003086948,0.00002062914,0.00006875073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001079924,0.000008806787,0.0001634411,0.00001801522,0.000003665429,0.00008151671,0.00001379999,0.00002484638,0.9992508,0.00007748196,0.00002367831,0.0002257579],"study_design_scores_gemma":[0.00001683302,0.0002072055,0.01921158,0.000006904846,0.00001185964,0.0006403954,0.00005629203,0.000535629,0.977553,0.00005363146,0.00170148,0.000005255831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921922,0.001493565,0.004007372,0.0000419863,0.00004566693,0.0000279216,0.000249816,0.00006644011,0.001875055],"genre_scores_gemma":[0.9952585,0.0004677902,0.001712526,0.0000403129,0.00001675382,0.00004821299,0.0005641691,0.0000222216,0.00186957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001513533,"threshold_uncertainty_score":0.005063295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005310044071566281,"score_gpt":0.1975574442451508,"score_spread":0.1922474001735845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}