{"id":"W2113990092","doi":"10.1016/j.celrep.2013.02.027","title":"UBXN1 Interferes with Rig-I-like Receptor-Mediated Antiviral Immune Response by Targeting MAVS","year":2013,"lang":"en","type":"article","venue":"Cell Reports","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Biology; Vesicular stomatitis virus; Innate immune system; TLR3; Viral replication; RIG-I; Virology; Interferon; Sendai virus; RNA virus; Cell biology; RNA; Virus; Immune system; Signal transducing adaptor protein; Pattern recognition receptor; Signal transduction; Toll-like receptor; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000704213,0.0003858869,0.0004888527,0.0001701151,0.0002395882,0.00007123986,0.0002414041,0.0003397433,0.005725813],"category_scores_gemma":[0.0002987936,0.0002957676,0.000138016,0.0001524361,0.0003583126,0.0002603701,0.0001651016,0.0005467343,0.003779463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000739894,"about_ca_system_score_gemma":0.0001313678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003373607,"about_ca_topic_score_gemma":0.000002515916,"domain_scores_codex":[0.9971887,0.0006764442,0.0007880462,0.0005655254,0.00007786045,0.0007034441],"domain_scores_gemma":[0.9983295,0.0003525653,0.0004485766,0.0006285111,0.0001923069,0.00004851306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002168987,0.0001529166,0.0009949569,0.00001382051,0.00009603859,0.00008030167,0.0003614463,2.917369e-7,0.8495175,0.000001778994,0.1457969,0.0008150772],"study_design_scores_gemma":[0.0006029491,0.000579452,0.001729948,0.00005699339,0.00001527139,0.0002565472,0.0005726382,0.000001223375,0.6647494,0.000005586019,0.3311148,0.0003151951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863654,0.006417203,0.00006985458,0.000309268,0.001437911,0.0004569516,0.00001476658,0.0002140704,0.004714521],"genre_scores_gemma":[0.9290984,0.000108829,0.0001094024,0.0002203755,0.00001909535,0.00006426995,0.0003649701,0.00005879178,0.06995589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1853179,"threshold_uncertainty_score":0.9999495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004455098920809896,"score_gpt":0.197877003571406,"score_spread":0.1934219046505961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}