{"id":"W2114007508","doi":"10.1093/toxsci/kfi203","title":"Effects of Atrazine on CYP19 Gene Expression and Aromatase Activity in Testes and on Plasma Sex Steroid Concentrations of Male African Clawed Frogs (Xenopus laevis)","year":2005,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Environmental Toxicology and Ecotoxicology","field":"Environmental Science","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institute of Environmental Health Sciences; College of Engineering, Michigan State University; Michigan State University","keywords":"Aromatase; Xenopus; Internal medicine; Endocrinology; Atrazine; Biology; Testosterone (patch); Gene expression; Sex steroid; African clawed frog; Gonad; Steroid; Gene; Hormone; Biochemistry; Pesticide; Ecology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113447,0.0002254073,0.0001689956,0.0002082632,0.0001676211,0.0002145958,0.0001151428,0.0001850962,0.001740828],"category_scores_gemma":[0.0001957223,0.0001712216,0.0002356352,0.0001005864,0.0002978164,0.0001454653,0.0001275757,0.0002598337,0.0002638786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002414044,"about_ca_system_score_gemma":0.0001413349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001460784,"about_ca_topic_score_gemma":0.002269473,"domain_scores_codex":[0.9998654,0.00003736377,0.000008521311,0.00003660061,0.00002509324,0.00002704995],"domain_scores_gemma":[0.9998424,0.00003083591,0.000061037,0.00001358404,0.00002317841,0.00002899131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003382236,0.00002214929,0.001565264,0.00002116715,0.00001233579,0.00004985073,0.00002965469,0.00005163668,0.9967263,0.00002040807,0.0000169637,0.001145971],"study_design_scores_gemma":[0.00004072229,0.001797197,0.09130973,0.000006641699,0.00005037148,0.0003108947,0.0001335723,0.0003850415,0.9046372,0.00004571419,0.001275219,0.00000769943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984341,0.000584092,0.0002238589,0.00004976595,0.000004865795,0.00000657616,0.0001648467,0.00002044004,0.0005113115],"genre_scores_gemma":[0.9954491,0.0006135723,0.0008455339,0.00005367402,0.000007875877,0.00002419545,0.000451101,0.00001349706,0.002541443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001740828,"threshold_uncertainty_score":0.005823612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406180190123558,"score_gpt":0.2430986974310832,"score_spread":0.2290368955298476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}