{"id":"W2114014715","doi":"10.1101/gr.1649303","title":"The Human Transcriptome Map Reveals Extremes in Gene Density, Intron Length, GC Content, and Repeat Pattern for Domains of Highly and Weakly Expressed Genes","year":2003,"lang":"en","type":"article","venue":"Genome Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":351,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health; U.S. National Library of Medicine; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Biology; Gene; Intron; Transcriptome; Genetics; Genome; Human genome; Gene expression; GC-content; Gene density; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001286429,0.0001354913,0.0002033491,0.00008199027,0.0002402982,0.00005736354,0.0002105202,0.0001208985,0.000002617773],"category_scores_gemma":[0.00006579387,0.0001112905,0.00005226681,0.00006244177,0.0002536623,0.00000408288,0.000128776,0.0001155211,4.599107e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002379441,"about_ca_system_score_gemma":0.00004245259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006559082,"about_ca_topic_score_gemma":0.0002662522,"domain_scores_codex":[0.9985117,0.0002186751,0.0003059996,0.0003759284,0.0001700582,0.0004176004],"domain_scores_gemma":[0.9992231,0.00007354167,0.0000635192,0.0003883245,0.0001688058,0.00008268622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004586786,0.00003566065,0.00712957,0.0001077524,0.00004070914,0.000002513706,0.0001619877,0.000003900017,0.9903474,0.0004441656,0.00005497199,0.001625469],"study_design_scores_gemma":[0.004273904,0.001287114,0.07568573,0.00006541291,0.00003911861,0.00004110257,0.00205036,0.0002035904,0.8861316,0.006494366,0.02313449,0.0005931507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903456,0.008122992,0.0005580208,0.0002403658,0.00003283071,0.0005613629,0.00005800607,0.00000292072,0.00007793282],"genre_scores_gemma":[0.9948733,0.003803268,0.0004849856,0.00002038116,0.00005676913,0.00006836902,0.00004896766,0.00002566246,0.00061832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1042158,"threshold_uncertainty_score":0.4538295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667008905673253,"score_gpt":0.3028698307907383,"score_spread":0.2561997417340057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}