{"id":"W2114014715","doi":"10.1101/gr.1649303","title":"The Human Transcriptome Map Reveals Extremes in Gene Density, Intron Length, GC Content, and Repeat Pattern for Domains of Highly and Weakly Expressed Genes","year":2003,"lang":"en","type":"article","venue":"Genome Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":351,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institutes of Health; U.S. National Library of Medicine; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Biology; Gene; Intron; Transcriptome; Genetics; Genome; Human genome; Gene expression; GC-content; Gene density; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009090523,0.000122508,0.0002609432,0.0005999299,0.0001915575,0.0003318818,0.00005962386,0.000135878,0.001870991],"category_scores_gemma":[0.000261636,0.0001092949,0.0002446841,0.0007867485,0.0001417387,0.0001419337,0.0002050196,0.0002166839,0.0007366345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001566347,"about_ca_system_score_gemma":0.0001602048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001213539,"about_ca_topic_score_gemma":0.001803556,"domain_scores_codex":[0.9999193,0.000007143561,0.000004359514,0.0000336843,0.00001982609,0.00001566004],"domain_scores_gemma":[0.9998807,0.00003515717,0.00002951633,0.00001468878,0.00001937115,0.00002046298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001083623,0.00003743663,0.09087549,0.0002085278,0.00009837115,0.0004935536,0.0004929196,0.0012322,0.8441475,0.001338509,0.002308072,0.05768376],"study_design_scores_gemma":[0.00002403241,0.0001295903,0.9350881,0.00002194403,0.00006333961,0.0009880256,0.0002335887,0.002828207,0.04666889,0.001950993,0.01197804,0.00002527022],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803926,0.0008604003,0.007329389,0.000119857,0.000006184846,0.00001108209,0.009096336,0.0002059202,0.00197815],"genre_scores_gemma":[0.9686747,0.0005660247,0.01134005,0.0001033074,0.00001083927,0.00003797235,0.01712994,0.00007793412,0.002059138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001870991,"threshold_uncertainty_score":0.006259084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04667008905673253,"score_gpt":0.3028698307907383,"score_spread":0.2561997417340057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}