{"id":"W2114018465","doi":"10.2217/17435889.2.3.375","title":"Mimicking Nature‘S Nanocarrier: Synthetic Low-Density Lipoprotein-Like Nanoparticles for Cancer-Drug Delivery","year":2007,"lang":"en","type":"letter","venue":"Nanomedicine","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Nanocarriers; Drug delivery; Nanotechnology; Nanoparticle; Drug; Targeted drug delivery; Low-density lipoprotein; Materials science; Chemistry; Pharmacology; Medicine; Cholesterol; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006887036,0.0005749667,0.0003209494,0.0002777231,0.0003924385,0.0005770502,0.0006431748,0.003822047,0.001722532],"category_scores_gemma":[0.001124306,0.0002113325,0.0002719251,0.000104063,0.0005823511,0.0007213686,0.0001965965,0.001528351,0.001543013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001084323,"about_ca_system_score_gemma":0.0003346303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002979428,"about_ca_topic_score_gemma":0.0005327102,"domain_scores_codex":[0.9995116,0.0001325656,0.00002709195,0.00006894416,0.0002239366,0.00003601554],"domain_scores_gemma":[0.9996943,0.0001548693,0.00003107135,0.00001889249,0.00007235516,0.00002848672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002748657,0.001196157,0.003442824,0.001512704,0.0001042866,0.02037251,0.0004877173,0.001593911,0.332911,0.02164974,0.3447717,0.2692088],"study_design_scores_gemma":[0.0006274296,0.001728483,0.00228645,0.00009070924,0.00007560018,0.02002899,0.0001124909,0.009396384,0.3670412,0.004269269,0.5942581,0.00008477631],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2259261,0.09683423,0.05436799,0.4688843,0.05468319,0.001167293,0.0006061433,0.001414588,0.09611624],"genre_scores_gemma":[0.6459964,0.04350975,0.03388842,0.1128986,0.01902637,0.0008213881,0.0006688392,0.0002469668,0.1429433],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003822047,"threshold_uncertainty_score":0.007867396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0080963283281021,"score_gpt":0.2512720196633176,"score_spread":0.2431756913352155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}