{"id":"W2114025189","doi":"10.1002/anie.200502179","title":"Thiooligosaccharide Conjugate Vaccines Evoke Antibodies Specific for Native Antigens","year":2005,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Alberta Glycomics Centre; University of Alberta","funders":"","keywords":"Glycoside; Conjugate; Antibody; Antigen; Antibody response; Conjugate vaccine; Virology; Biology; Immunology; Chemistry; Immunogenicity; Stereochemistry; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002313427,0.0005518103,0.0002874646,0.0002324374,0.00008879097,0.0003339117,0.0001360052,0.0004920226,0.001197653],"category_scores_gemma":[0.0002140351,0.000145744,0.0002747437,0.0001818225,0.0002396763,0.0003046339,0.0001980491,0.0006252934,0.0002829439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002524786,"about_ca_system_score_gemma":0.0001527938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000215921,"about_ca_topic_score_gemma":0.0003439853,"domain_scores_codex":[0.9998572,0.00003075788,0.00001284228,0.00002758192,0.00003676879,0.00003487676],"domain_scores_gemma":[0.9998728,0.00003127142,0.00003305441,0.00001988517,0.00001965605,0.00002331357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002107275,0.00005641424,0.0001636904,0.00006558668,0.00001385621,0.00001684775,0.000009028947,0.00009160978,0.9958215,0.0001720825,0.0000719826,0.003306654],"study_design_scores_gemma":[0.0000283951,0.00144603,0.001196253,0.00000620227,0.00002712877,0.0001156118,0.000008518831,0.0002637921,0.9957782,0.00005285255,0.001073647,0.000003339581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903013,0.001678405,0.00433796,0.00008518923,0.00008366414,0.00007357293,0.000108064,0.0001038744,0.00322802],"genre_scores_gemma":[0.9944728,0.001010827,0.002358415,0.00008136628,0.00002480098,0.00003488944,0.0001641093,0.0000188087,0.001833964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001197653,"threshold_uncertainty_score":0.004006565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02160439450004988,"score_gpt":0.3042457743857079,"score_spread":0.282641379885658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}