{"id":"W2114032025","doi":"10.1152/ajpendo.00045.2014","title":"Ca<sup>2+</sup>signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells","year":2014,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Ionomycin; Endocytosis; Exocytosis; Cell biology; Protein kinase C; Chemistry; Intracellular; BAPTA; AMPK; Brefeldin A; Protein kinase A; Cell; Biology; Biochemistry; Signal transduction; Kinase; Endoplasmic reticulum; Golgi apparatus; Secretion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001020984,0.0003550684,0.0004162149,0.0001826661,0.0001533673,0.0003676859,0.0002299485,0.0002940182,0.002547644],"category_scores_gemma":[0.00008761915,0.0001160113,0.00038329,0.0002200549,0.0001843936,0.0003177338,0.000235508,0.0004777816,0.0009623826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003482188,"about_ca_system_score_gemma":0.0002442528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007641911,"about_ca_topic_score_gemma":0.000973894,"domain_scores_codex":[0.9998901,0.00001030236,0.00001549538,0.00002090142,0.00002843751,0.00003470613],"domain_scores_gemma":[0.9999461,0.000007524955,0.00001236799,0.00000574193,0.000009592356,0.00001868718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000326642,0.00002267075,0.0001105793,0.00007986224,0.000005747274,0.00006052767,0.000008575679,0.00003976731,0.9979594,0.00009237476,0.0001450602,0.001148772],"study_design_scores_gemma":[0.0000510642,0.0001642769,0.005325701,0.000009827242,0.00001757129,0.0001636035,0.00003470987,0.0007388061,0.9886885,0.00005213486,0.004748736,0.000005026162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833697,0.004640106,0.003412085,0.0006170462,0.0001442363,0.00006219097,0.00156226,0.000306607,0.005885762],"genre_scores_gemma":[0.9865469,0.001759128,0.002626789,0.0002934921,0.00003911366,0.00009919392,0.001427338,0.00007671124,0.007131423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002547644,"threshold_uncertainty_score":0.008522749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008257710783326924,"score_gpt":0.2392841483178934,"score_spread":0.2310264375345664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}