{"id":"W2114043064","doi":"10.1056/nejmoa1100102","title":"<i>STAT1</i> Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis","year":2011,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":656,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"ZonMw; European Commission","keywords":"Chronic mucocutaneous candidiasis; Mucocutaneous zone; Medicine; Autoimmunity; Immunology; Candida albicans; Mucous membrane; Dermatology; Genetics; Immune system; Pathology; Disease; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005582415,0.0001529697,0.0004188463,0.0002756648,0.00008898498,0.000003880217,0.0002445582,0.0001092738,0.001310046],"category_scores_gemma":[0.0002043767,0.000105456,0.00007475909,0.0002070152,0.0002698772,0.0001192809,0.00002051554,0.0004821857,0.0000419489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008643181,"about_ca_system_score_gemma":0.000470634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001407072,"about_ca_topic_score_gemma":0.0001778511,"domain_scores_codex":[0.9986906,0.0001539248,0.0006476486,0.0001190863,0.00006914858,0.0003195645],"domain_scores_gemma":[0.999286,0.0001663753,0.0003062968,0.0001446684,0.00007473605,0.00002191426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002087452,0.0004857548,0.002803684,0.00004397162,0.0003156625,0.001259986,0.05144907,0.0001228165,0.3401494,0.001278816,0.001417512,0.5985859],"study_design_scores_gemma":[0.2857792,0.01322565,0.07020888,0.002045646,0.0008798204,0.03444731,0.01475965,0.00005297517,0.1098101,0.00754033,0.4600378,0.001212687],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.92852,0.06302478,0.0003483739,0.001194028,0.001967564,0.0001210333,0.000003303012,0.00001359998,0.004807282],"genre_scores_gemma":[0.9983413,0.0005663757,0.00004113232,0.000135106,0.00007820994,0.000001521193,0.00001036692,0.00001137552,0.0008145899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5973732,"threshold_uncertainty_score":0.9996029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01424162122891641,"score_gpt":0.231717055886209,"score_spread":0.2174754346572926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}