{"id":"W2114113329","doi":"10.1002/jps.20267","title":"Down‐regulation of aryl hydrocarbon receptor–regulated genes by tumor necrosis factor‐α and lipopolysaccharide in murine hepatoma hepa 1c1c7 cells","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Aryl hydrocarbon receptor; Lipopolysaccharide; Tumor necrosis factor alpha; Chemistry; Gene; Aryl; Cell biology; Receptor; Microbiology; Biochemistry; Biology; Immunology; Transcription factor; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007663217,0.0001382372,0.0003122501,0.0002512676,0.0001104908,0.0000255805,0.0002116825,0.0001093864,0.000261291],"category_scores_gemma":[0.00006962844,0.0001039647,0.00007814073,0.0002960107,0.0005074198,0.0003994638,0.00004966858,0.0002381747,0.00001262761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006594432,"about_ca_system_score_gemma":0.000113111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001536169,"about_ca_topic_score_gemma":0.000008054903,"domain_scores_codex":[0.9986413,0.0001141971,0.0006647708,0.0001645294,0.0001379818,0.0002771825],"domain_scores_gemma":[0.9992794,0.0001358362,0.0003862481,0.00006888957,0.00007970571,0.00004987812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003176864,0.0001133217,0.004890298,0.00001574423,0.00003266327,0.000003252695,0.00023226,0.0001136181,0.9879954,0.0001242286,0.00005734374,0.00610416],"study_design_scores_gemma":[0.001479165,0.0003374218,0.009538106,0.00008522306,0.00002617629,0.00008316716,0.00008045435,0.0002025735,0.9864795,0.0003118914,0.001261348,0.0001149523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944931,0.004178979,0.0000523688,0.00071757,0.0003972946,0.0001132684,0.000005536705,0.000008737299,0.000033089],"genre_scores_gemma":[0.9988433,0.0008976949,0.0001205231,0.00006372591,0.00002622297,0.000001305269,0.000002652485,0.000005265242,0.00003932565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005989207,"threshold_uncertainty_score":0.4239558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01652991948225609,"score_gpt":0.2810014238482627,"score_spread":0.2644715043660066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}