{"id":"W2114288259","doi":"10.1073/pnas.0905729106","title":"Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; Toronto General Hospital; University Health Network; University of Toronto","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Transplantation; Induced pluripotent stem cell; Embryonic stem cell; Stem cell; Progenitor cell; Cell therapy; Cell; Cell biology; Biology; Medicine; Cancer research; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008512195,0.000105006,0.0001392323,0.0001010251,0.0001589656,0.00002988803,0.000349358,0.000106752,0.00000295426],"category_scores_gemma":[0.00008438277,0.00007641021,0.00005894568,0.0003000923,0.0003467211,0.00003313208,0.0001494505,0.0001401591,9.287864e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002109452,"about_ca_system_score_gemma":0.00003418858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003587447,"about_ca_topic_score_gemma":8.511861e-8,"domain_scores_codex":[0.9985378,0.00001865629,0.0002747394,0.0002902256,0.0007199065,0.0001586615],"domain_scores_gemma":[0.9993307,0.00003722556,0.0002628938,0.00001109175,0.0003117364,0.00004634713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001635445,0.00001694789,0.001250148,0.00002233079,0.00001161901,3.300855e-9,0.00009527204,0.00004679865,0.996146,0.0001757338,0.0002210272,0.001997788],"study_design_scores_gemma":[0.0001473414,0.0001498119,0.04228898,0.00004040333,0.000009456307,0.000001588281,0.0002723698,0.0002037936,0.9560944,0.0005851781,0.0001326811,0.00007404273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975442,0.0001910966,0.00001478773,0.0007415896,0.00002115102,0.0002001648,0.0000251887,0.000005722936,0.001256051],"genre_scores_gemma":[0.9988346,0.00006212939,0.000616419,0.00006322811,0.0001085792,0.000004821439,0.00000239501,0.00000386471,0.0003040121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04103883,"threshold_uncertainty_score":0.3115918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03278048826284124,"score_gpt":0.2899441099317879,"score_spread":0.2571636216689467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}