{"id":"W2114369115","doi":"10.1158/0008-5472.can-12-0157","title":"Accumulation of Multipotent Progenitors with a Basal Differentiation Bias during Aging of Human Mammary Epithelia","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Cancer Institute; National Institute on Aging; U.S. Department of Energy; Laboratory Directed Research and Development; U.S. Department of Defense","keywords":"Progenitor cell; Basal (medicine); Cell biology; Biology; Progenitor; Cellular differentiation; Stem cell; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001738237,0.0001174508,0.0001935118,0.0004301168,0.0001554231,0.0002188069,0.00008518169,0.0001091837,0.0004791695],"category_scores_gemma":[0.0001782604,0.000125687,0.0001584136,0.0002477915,0.0001101235,0.0001244042,0.0002663783,0.0001885129,0.0002424121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009119158,"about_ca_system_score_gemma":0.0001406031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005985496,"about_ca_topic_score_gemma":0.0006764657,"domain_scores_codex":[0.9999095,0.00001254509,0.00001397817,0.00002164415,0.00002397973,0.00001833151],"domain_scores_gemma":[0.9998623,0.00001775798,0.00002754111,0.00003515192,0.0000264624,0.00003073904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002044506,0.00002599085,0.01556172,0.00003063417,0.00001191655,0.0001798596,0.0001094537,0.00006302025,0.9786178,0.0000636917,0.00003694805,0.005094474],"study_design_scores_gemma":[0.00001978061,0.001245275,0.4925785,0.00002641783,0.0001072359,0.004491486,0.0003673646,0.0006901758,0.493458,0.0002293168,0.00676765,0.00001886567],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971985,0.001516484,0.0007181477,0.00001687217,0.000004212105,0.00001209081,0.0002142198,0.000009513693,0.0003099704],"genre_scores_gemma":[0.9964595,0.001046514,0.0008752171,0.00003302392,0.000007687197,0.00002446441,0.0007822161,0.000006541721,0.0007647605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005985496,"threshold_uncertainty_score":0.001602948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2630793017690571,"score_gpt":0.4608576628779437,"score_spread":0.1977783611088865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}