{"id":"W2114457800","doi":"10.1177/00912700222011193","title":"Multiple‐Dose, Safety, Pharmacokinetics, and Pharmacodynamics of a New Selective Estrogen Receptor Modulator, ERA‐923, in Healthy Postmenopausal Women","year":2002,"lang":"en","type":"article","venue":"The Journal of Clinical Pharmacology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Pharmacokinetics; Medicine; Pharmacodynamics; Tolerability; Placebo; Adverse effect; Selective estrogen receptor modulator; Internal medicine; Estrogen; Tamoxifen; Pharmacology; Breast cancer; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004216575,0.0004309667,0.0006384608,0.0001862547,0.0002401423,0.0001932443,0.0001655372,0.0004166804,0.0007851925],"category_scores_gemma":[0.0008118945,0.0002996486,0.0002792908,0.0001563105,0.0003569991,0.0002318349,0.0001178189,0.0007415296,0.0002024757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001775207,"about_ca_system_score_gemma":0.0002159408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005704475,"about_ca_topic_score_gemma":0.00108389,"domain_scores_codex":[0.9998036,0.00008568744,0.00001171327,0.0000343515,0.00004570411,0.00001907689],"domain_scores_gemma":[0.9997255,0.00006837667,0.00009581185,0.00002099232,0.00002214349,0.00006712939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2166905,0.009952991,0.05527661,0.0006233045,0.001161695,0.001008792,0.0007815278,0.001170645,0.5373512,0.00009838324,0.0008610918,0.1750234],"study_design_scores_gemma":[0.02940586,0.5814373,0.3237156,0.00004123589,0.001656286,0.002767725,0.0003401886,0.002091717,0.05485421,0.0002108761,0.003406552,0.00007247968],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984537,0.001031062,0.0001748785,0.00004014157,0.000006966976,0.00003465558,0.00006810069,0.00001687878,0.0001735811],"genre_scores_gemma":[0.9979778,0.0008815777,0.0003683745,0.00008540967,0.00003551286,0.0000486445,0.0001418204,0.000007562278,0.0004532612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007851925,"threshold_uncertainty_score":0.002626777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02209906425235965,"score_gpt":0.3476892674425801,"score_spread":0.3255902031902205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}