{"id":"W2114477384","doi":"10.1128/mcb.26.10.3976-3985.2006","title":"Uncoupling the Pleiotropic Phenotypes of <i>clk-1</i> with tRNA Missense Suppressors in <i>Caenorhabditis elegans</i>","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institutes of Health; National Center for Research Resources; McGill University","keywords":"Caenorhabditis elegans; Biology; Phenotype; Missense mutation; Mutant; Genetics; Gene; Suppressor; Mutation; Transfer RNA; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001163987,0.0008141955,0.0002841609,0.0004175776,0.0003024819,0.0003261229,0.0004101281,0.0003546193,0.0007532018],"category_scores_gemma":[0.0002141651,0.0002527146,0.0004182156,0.0001787868,0.0003624617,0.000140241,0.0005115925,0.0006107998,0.0004093245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004806293,"about_ca_system_score_gemma":0.000402919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002216929,"about_ca_topic_score_gemma":0.005482547,"domain_scores_codex":[0.9997757,0.00001971843,0.00003965108,0.0000500228,0.00007518843,0.00003965505],"domain_scores_gemma":[0.9996217,0.00006583735,0.0001387992,0.00004358419,0.00003506061,0.00009491288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002401786,0.00001343597,0.0002063392,0.00001145982,0.00000335574,0.00006895563,0.000007526663,0.00004495552,0.9991996,0.00003041353,0.00001746352,0.0003724588],"study_design_scores_gemma":[0.00001746387,0.0001149908,0.00928755,0.00001056332,0.00002171127,0.0004977692,0.0000375027,0.00123101,0.9875108,0.00002910003,0.001229054,0.00001261061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996277,0.0003084637,0.001834974,0.00005419123,0.00003182574,0.00002437196,0.000385698,0.000132139,0.0009512598],"genre_scores_gemma":[0.9945579,0.0002082494,0.002935535,0.0000555858,0.000007835337,0.00002774898,0.0006161469,0.0001113733,0.001479636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002216929,"threshold_uncertainty_score":0.004408062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003263319082235187,"score_gpt":0.1761478892208473,"score_spread":0.1728845701386122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}