{"id":"W2114562795","doi":"10.1111/j.1365-2958.2004.04448.x","title":"The contribution of MvfR to <i>Pseudomonas aeruginosa</i> pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing‐regulated genes are modulated without affecting <i>lasRI</i>, <i>rhlRI</i> or the production of <i>N</i>‐acyl‐ <scp>l</scp>‐homoserine lactones","year":2005,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":425,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"","keywords":"Quorum sensing; Virulence; Pseudomonas aeruginosa; Biology; Homoserine; Microbiology; Gene; Mutant; Transcription (linguistics); Transcriptional regulation; Regulator; Transcription factor; Cell biology; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001302299,0.0004339793,0.0002885745,0.000179934,0.0001688595,0.0004360849,0.0002422439,0.0004384291,0.0004922082],"category_scores_gemma":[0.0001961349,0.0001662921,0.0003604538,0.0000841198,0.000329137,0.0003602818,0.0003012886,0.0005240666,0.0002320965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005069722,"about_ca_system_score_gemma":0.0002525214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001362347,"about_ca_topic_score_gemma":0.001012407,"domain_scores_codex":[0.9997558,0.00002590908,0.00001390848,0.00007222262,0.000070823,0.00006136122],"domain_scores_gemma":[0.999821,0.00003169602,0.00006212624,0.00002466832,0.00002343085,0.00003704601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001863908,0.000004577253,0.000160299,0.000007785769,7.368898e-7,0.00001340602,0.000006529955,0.00001941436,0.9993387,0.00003713632,0.000004006934,0.0003888525],"study_design_scores_gemma":[0.000005190372,0.0001333743,0.01030031,0.000005409753,0.000009865625,0.0002971203,0.00003297268,0.001281734,0.9871053,0.00007987526,0.0007422121,0.00000663672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990692,0.001380322,0.006317513,0.0002466819,0.00001376446,0.00001913062,0.0002265585,0.0001112303,0.0009928668],"genre_scores_gemma":[0.9961554,0.0003826827,0.002194882,0.00006747321,0.00001164719,0.00001669353,0.0002692976,0.00002225429,0.0008795333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001362347,"threshold_uncertainty_score":0.003678322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006073895966956263,"score_gpt":0.206747144132863,"score_spread":0.2006732481659068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}