{"id":"W2114563370","doi":"10.1097/00007890-200104150-00020","title":"HuM291(NUVION), A HUMANIZED Fc RECEPTOR-NONBINDING ANTIBODY AGAINST CD3, ANERGIZES PERIPHERAL BLOOD T CELLS AS PARTIAL AGONIST OF THE T CELL RECEPTOR1","year":2001,"lang":"en","type":"article","venue":"Transplantation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"National Institutes of Health","keywords":"T-cell receptor; CD3; Agonist; Antibody; T cell; Immunology; Biology; Monoclonal antibody; Receptor; Cell biology; Antigen; Immune system; CD8; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001060904,0.0004311459,0.0002091769,0.0002112961,0.0001143039,0.000159712,0.0002302381,0.0003114815,0.001890261],"category_scores_gemma":[0.0001009998,0.00007923855,0.0001863414,0.0001103712,0.000136336,0.00008749182,0.000150297,0.0003468099,0.0004905416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002339493,"about_ca_system_score_gemma":0.0001493812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003998789,"about_ca_topic_score_gemma":0.0005509531,"domain_scores_codex":[0.9998987,0.00002404764,0.000005208221,0.0000177159,0.00002451549,0.0000297579],"domain_scores_gemma":[0.9999375,0.00001799177,0.0000155212,0.000006322299,0.000005045049,0.00001764838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001812761,0.00004638985,0.0001634503,0.00003626086,0.00000395843,0.0000682467,0.000007200569,0.00008017664,0.9966164,0.0000464786,0.00007026584,0.002679904],"study_design_scores_gemma":[0.00005137132,0.001168602,0.002294786,0.000006932,0.00001386164,0.0007538637,0.00000824024,0.0005911094,0.991553,0.00002550499,0.003529883,0.000002798144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912144,0.003046233,0.002867091,0.00006839394,0.00002356793,0.00005358788,0.0002674717,0.0001082259,0.002351028],"genre_scores_gemma":[0.9939486,0.001036607,0.001963332,0.0000636241,0.00001337761,0.00004314006,0.0007417853,0.00001306448,0.002176469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001890261,"threshold_uncertainty_score":0.006323576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0165021016914292,"score_gpt":0.2942568813136187,"score_spread":0.2777547796221895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}