{"id":"W2114563370","doi":"10.1097/00007890-200104150-00020","title":"HuM291(NUVION), A HUMANIZED Fc RECEPTOR-NONBINDING ANTIBODY AGAINST CD3, ANERGIZES PERIPHERAL BLOOD T CELLS AS PARTIAL AGONIST OF THE T CELL RECEPTOR1","year":2001,"lang":"en","type":"article","venue":"Transplantation","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"National Institutes of Health","keywords":"T-cell receptor; CD3; Agonist; Antibody; T cell; Immunology; Biology; Monoclonal antibody; Receptor; Cell biology; Antigen; Immune system; CD8; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002710203,0.0002516867,0.0003781364,0.0001083974,0.0003547246,0.00004105145,0.0002235049,0.0001403037,0.001415459],"category_scores_gemma":[0.00001410192,0.0001810638,0.0002602437,0.0003499156,0.0002355505,0.0001284265,0.0000225207,0.0003414594,0.0001449367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004181544,"about_ca_system_score_gemma":0.0001477328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003968833,"about_ca_topic_score_gemma":0.0000730278,"domain_scores_codex":[0.99785,0.000185858,0.0004937292,0.0003495484,0.0006871352,0.0004337212],"domain_scores_gemma":[0.9991713,0.0001050404,0.0001643309,0.0002675493,0.0001361714,0.0001555754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002687698,0.0003970576,0.0146762,0.0004127336,0.00009819974,0.00009537967,0.001963542,0.00003454136,0.978053,0.0002098052,0.0003333678,0.001038496],"study_design_scores_gemma":[0.004710312,0.000705201,0.01376051,0.0003344937,0.0003380445,0.0001389556,0.0003317397,0.0001873493,0.9659442,0.000030182,0.01322415,0.0002948845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865593,0.0002327306,0.00008761135,0.0006517867,0.0003611671,0.0005384593,0.00009643967,0.00005303051,0.01141944],"genre_scores_gemma":[0.9870332,0.00416998,0.0004180257,0.0002777507,0.0003573862,0.00001955771,0.0006131218,0.00003677165,0.007074174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01289078,"threshold_uncertainty_score":0.9994974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0165021016914292,"score_gpt":0.2942568813136187,"score_spread":0.2777547796221895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}