{"id":"W2114592067","doi":"10.1158/0008-5472.can-05-0765","title":"Low-dose Metronomic Combined with Intermittent Bolus-dose Cyclophosphamide Is an Effective Long-term Chemotherapy Treatment Strategy","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; Oncosuisse; National Cancer Institute; National Science Foundation; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Cyclophosphamide; Medicine; Regimen; Toxicity; Chemotherapy; Bolus (digestion); Pharmacology; Nitrogen mustard; Oncology; Internal medicine; Urology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007769317,0.0002671474,0.0003289726,0.0002013827,0.0000892018,0.0001961563,0.0002391839,0.0001253606,0.0007674123],"category_scores_gemma":[0.00005962352,0.00005312754,0.00015077,0.0001807563,0.0001275511,0.0001294486,0.0001367397,0.0004258651,0.0001591659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000218403,"about_ca_system_score_gemma":0.0001599465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002320432,"about_ca_topic_score_gemma":0.001060119,"domain_scores_codex":[0.9999309,0.00001365432,0.0000055775,0.00001739556,0.00001671755,0.00001574195],"domain_scores_gemma":[0.9999561,0.000005183002,0.00001577787,0.000009219051,0.000002993833,0.00001074692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001031236,0.0007033499,0.001281764,0.0001750635,0.00003876736,0.0000767454,0.00001793215,0.0004838837,0.938264,0.0001971755,0.0004141488,0.05731588],"study_design_scores_gemma":[0.0005245221,0.02663232,0.03330567,0.00005368945,0.0001849715,0.001557154,0.00002836987,0.002586015,0.9154834,0.0001281192,0.01948756,0.00002831073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843634,0.008148518,0.005069095,0.0001123351,0.00006680739,0.0001200057,0.000180774,0.0001599935,0.001779098],"genre_scores_gemma":[0.9956347,0.001330947,0.001945431,0.00003755717,0.00002155296,0.00005511299,0.0001956453,0.00001006784,0.0007689953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007674123,"threshold_uncertainty_score":0.002567232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0321332893579331,"score_gpt":0.3684955812790895,"score_spread":0.3363622919211564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}