{"id":"W2114606818","doi":"10.1517/14656566.2012.667073","title":"A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain","year":2012,"lang":"en","type":"article","venue":"Expert Opinion on Pharmacotherapy","topic":"Opioid Use Disorder Treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Medicine; Tolerability; Hydrocodone; Anesthesia; Acetaminophen; Osteoarthritis; Transdermal; Analgesic; Buprenorphine; Adverse effect; Opioid; Clinical endpoint; Randomized controlled trial; Surgery; Oxycodone; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00164605,0.0006987762,0.001363787,0.0004127198,0.0001732071,0.00005485017,0.000235664,0.0001480712,0.001981648],"category_scores_gemma":[0.0000383712,0.0004942701,0.0002034702,0.0004532485,0.00006104662,0.0003237812,0.00003722808,0.0003160395,0.0002110175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004651735,"about_ca_system_score_gemma":0.0001285757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005342877,"about_ca_topic_score_gemma":0.00001963572,"domain_scores_codex":[0.9948831,0.001375815,0.0009384304,0.0008215631,0.001218704,0.0007623461],"domain_scores_gemma":[0.9979461,0.000539347,0.0002632524,0.000563129,0.0001704613,0.0005176387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8932367,0.008423379,0.02667657,0.00009012326,0.0007927963,0.00002886011,0.03615662,0.00007731995,0.002937242,0.000003921164,0.001733221,0.02984326],"study_design_scores_gemma":[0.969182,0.008953772,0.003686631,0.001022419,0.0001166137,0.000004380812,0.002973295,0.001015032,0.006534768,6.61656e-7,0.005830707,0.0006797953],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801987,0.003663715,0.0002318765,0.00090199,0.001018804,0.01348788,0.00009185307,0.0001950429,0.0002101811],"genre_scores_gemma":[0.9932905,0.0003997239,0.0006222031,0.001546179,0.0005885944,0.002530849,0.0005737829,0.000160275,0.0002878232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07594524,"threshold_uncertainty_score":0.9997509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04890670844190818,"score_gpt":0.3569356426387557,"score_spread":0.3080289341968475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}