{"id":"W2114618700","doi":"10.1369/jhc.6a7129.2006","title":"Hypoxia-inducible Factors in the First Trimester Human Lung","year":2006,"lang":"en","type":"article","venue":"Journal of Histochemistry & Cytochemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; SickKids Foundation; University of Toronto; Hospital for Sick Children; Canadian Institutes of Health Research","funders":"","keywords":"Aryl hydrocarbon receptor nuclear translocator; Biology; Vascular endothelial growth factor; Epithelium; Hypoxia (environmental); Mesenchyme; Hypoxia-inducible factors; HIF1A; Lung; Angiogenesis; Organogenesis; Parenchyma; Immunohistochemistry; Hydroxylation; Pathology; Endocrinology; Internal medicine; Cancer research; Transcription factor; Chemistry; Immunology; Biochemistry; Medicine; Gene; VEGF receptors; Aryl hydrocarbon receptor; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272462,0.0001172146,0.0001147614,0.0003803756,0.0001043584,0.0002565604,0.00008988276,0.0001269828,0.0009706264],"category_scores_gemma":[0.0002651226,0.000117632,0.00008741517,0.0002031827,0.0001173447,0.00007260507,0.00009915093,0.0001935619,0.0003721341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003129999,"about_ca_system_score_gemma":0.0002008496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0022518,"about_ca_topic_score_gemma":0.001559458,"domain_scores_codex":[0.9999193,0.00001190639,0.000006781174,0.0000207149,0.00002869782,0.00001259758],"domain_scores_gemma":[0.9999102,0.00001987628,0.00002896807,0.000009114765,0.00001934541,0.00001253338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005631698,0.00002174754,0.01151921,0.0001554736,0.00001484545,0.0007272491,0.0001590184,0.0001016607,0.9570087,0.0004788238,0.000418775,0.0288313],"study_design_scores_gemma":[0.00003182252,0.0004065095,0.2580368,0.00007890134,0.00007793386,0.0104674,0.000292631,0.0007655549,0.6723544,0.0006191859,0.05685188,0.00001707186],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9373359,0.04231773,0.007180671,0.0002904505,0.00006457783,0.0001196092,0.002804008,0.0001901958,0.009696874],"genre_scores_gemma":[0.9772139,0.01017779,0.004988595,0.00009366617,0.00002097278,0.00009420393,0.002324631,0.00002588267,0.005060507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0022518,"threshold_uncertainty_score":0.004477382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00951087715775981,"score_gpt":0.2488233527975885,"score_spread":0.2393124756398287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}