{"id":"W2114639903","doi":"10.1055/s-2004-823104","title":"The Pathogenesis of Nonalcoholic Steatohepatitis and Other Fatty Liver Diseases: A Four-Step Model including the Role of Lipid Release and Hepatic Venular Obstruction in the Progression to Cirrhosis","year":2004,"lang":"en","type":"review","venue":"Seminars in Liver Disease","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"","keywords":"Steatosis; Cirrhosis; Steatohepatitis; Fatty liver; Nonalcoholic fatty liver disease; Medicine; Fibrosis; Necrosis; Internal medicine; Pathology; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003412541,0.000447049,0.0009404833,0.0002192642,0.0001871324,0.000039649,0.0002849218,0.0001275755,0.000008157943],"category_scores_gemma":[0.000201474,0.0002362766,0.0003628056,0.0004692404,0.0002906802,0.00008519825,0.000248223,0.0002155288,0.000002318872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002102057,"about_ca_system_score_gemma":0.0003774301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003465388,"about_ca_topic_score_gemma":0.00004921369,"domain_scores_codex":[0.9974442,0.0004612008,0.0006552897,0.0005378238,0.0005819065,0.0003196556],"domain_scores_gemma":[0.997917,0.000567525,0.0004009919,0.0007335081,0.00007398403,0.0003070082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0003197789,0.0009906684,0.1697433,0.01189099,0.0002625006,0.000227924,0.001783785,0.00003894094,0.000002168375,0.0002578575,0.00002505712,0.8144571],"study_design_scores_gemma":[0.00509456,0.001184798,0.662077,0.2503356,0.02724114,0.0001521776,0.001923295,0.009052584,0.00002303921,0.001437965,0.03989519,0.00158276],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1360685,0.8602145,0.000004233858,0.00007190445,0.00003584017,0.002974959,0.0006002325,0.000009127453,0.00002067827],"genre_scores_gemma":[0.2261005,0.7723879,0.0001584016,0.00007196607,0.00005352188,0.001134288,0.00004251496,0.00004635147,0.000004566199],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8128743,"threshold_uncertainty_score":0.9635081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03063878090072775,"score_gpt":0.3078000392970124,"score_spread":0.2771612583962847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}