{"id":"W2114656820","doi":"10.1186/gb-2010-11-3-r29","title":"Genome-wide functional analysis of human 5' untranslated region introns","year":2010,"lang":"en","type":"article","venue":"Genome biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institute for Advanced Research; National Heart, Lung, and Blood Institute; W. M. Keck Foundation","keywords":"Intron; Untranslated region; Biology; Genetics; Gene; Human genome; Three prime untranslated region; Group II intron; Minor spliceosome; Genome; RNA splicing; Five prime untranslated region; Exon; Computational biology; Alternative splicing; Messenger RNA; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003646087,0.0002207244,0.0003097225,0.0007563723,0.0002535264,0.0002854886,0.0002324589,0.000264847,0.0006625635],"category_scores_gemma":[0.0005262445,0.00008508484,0.00060818,0.0009821741,0.0001319532,0.0001167451,0.000205445,0.0003132561,0.0002594445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000155549,"about_ca_system_score_gemma":0.0002304661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009550592,"about_ca_topic_score_gemma":0.001770126,"domain_scores_codex":[0.9998128,0.00002401038,0.00001375609,0.00009225659,0.00003596234,0.00002122324],"domain_scores_gemma":[0.9996932,0.0001568158,0.00007152501,0.00001864913,0.00003328862,0.00002663702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001744602,0.0002403099,0.4358013,0.001318098,0.0009686355,0.001434752,0.0003334757,0.01330685,0.4753382,0.0013524,0.002160684,0.06600068],"study_design_scores_gemma":[0.00005331151,0.0002862381,0.9201764,0.0000676728,0.0006307976,0.002032517,0.0001435602,0.02624792,0.04064573,0.001105675,0.008577441,0.00003271373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868182,0.001934229,0.004647046,0.00005723702,0.000008654586,0.00001676397,0.005819706,0.00009271517,0.000605511],"genre_scores_gemma":[0.9765692,0.0005265013,0.008254662,0.0000721021,0.00001347704,0.00002830693,0.01429229,0.00003046457,0.0002128682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009550592,"threshold_uncertainty_score":0.002216518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566774221585735,"score_gpt":0.2714321972920294,"score_spread":0.2557644550761721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}