{"id":"W2114673327","doi":"10.1091/mbc.e12-09-0705","title":"COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux","year":2013,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Trace Elements in Health","field":"Nursing","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University; Montreal Neurological Institute and Hospital; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"ATP7A; Biology; Cytosol; Menkes disease; Cell biology; Mitochondrion; Efflux; Cytochrome c oxidase; Signal transduction; Copper; Golgi apparatus; Biochemistry; ATPase; Chemistry; Enzyme; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001233966,0.0003913131,0.0002114095,0.000238253,0.0003337503,0.0004835817,0.0002138266,0.0002615928,0.001829181],"category_scores_gemma":[0.0001914733,0.0001396968,0.0002369475,0.0001423184,0.0002744738,0.0002790851,0.0003811834,0.0004010618,0.000678303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004891521,"about_ca_system_score_gemma":0.0002718836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009279153,"about_ca_topic_score_gemma":0.001341786,"domain_scores_codex":[0.9998935,0.0000167349,0.000007914843,0.00002300968,0.00003200664,0.00002673113],"domain_scores_gemma":[0.9997535,0.0000374573,0.00006734995,0.00002209007,0.00003807766,0.00008156309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001097283,0.00001261288,0.0006993935,0.00002971937,0.00000544785,0.0001891437,0.00001794525,0.0000240044,0.9976914,0.0002789584,0.0000541334,0.0008873937],"study_design_scores_gemma":[0.00001642602,0.00007591989,0.009620908,0.000007845758,0.0000092207,0.0004408317,0.00004995161,0.0006193657,0.98558,0.00008856047,0.003487471,0.00000360185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989015,0.001987029,0.006146781,0.00018838,0.00005768724,0.00002542739,0.000496908,0.00007075124,0.002012054],"genre_scores_gemma":[0.9936447,0.0008309712,0.001878257,0.00002441448,0.00001660928,0.00001835798,0.000820393,0.00002266631,0.002743527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001829181,"threshold_uncertainty_score":0.006119192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008625801058406355,"score_gpt":0.2341173334940583,"score_spread":0.225491532435652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}