{"id":"W2114808093","doi":"10.25011/cim.v31i4.4823","title":"SPECIES-SPECIFIC SEQUENCE VARIATION OF PORCINE ISLET AMYLOID POLYPEPTIDE REDUCES ITS AMYLOIDOGENICITY AND MAY CONTRIBUTE TO IMPROVED FUNCTION AND SURVIVAL OF PIG ISLET XENOGRAFTS","year":2008,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Islet; Thioflavin; Amyloid (mycology); Peptide; Apoptosis; Internal medicine; Endocrinology; Chemistry; Insulin; Biology; Biochemistry; Medicine; Alzheimer's disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003211361,0.0002643991,0.0001723614,0.0001571712,0.0001157791,0.0003420439,0.0003071542,0.0003642532,0.001975711],"category_scores_gemma":[0.0002435817,0.0001354805,0.0002954294,0.0001229659,0.0001626233,0.000182775,0.0002170745,0.0005453333,0.0005700869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001589272,"about_ca_system_score_gemma":0.0001206489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001583371,"about_ca_topic_score_gemma":0.0002044578,"domain_scores_codex":[0.9998108,0.00004710109,0.00002354211,0.00005321563,0.00003554377,0.00002981945],"domain_scores_gemma":[0.9997709,0.00004704489,0.00008195602,0.00004028037,0.00002253692,0.00003722087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000619542,0.00003890058,0.0002730822,0.00001437064,0.000007504817,0.00004435726,0.000007771512,0.00003658656,0.998531,0.00003194502,0.00003024955,0.0009222301],"study_design_scores_gemma":[0.00006236675,0.001583468,0.02518871,0.00002564567,0.00008598014,0.001870643,0.00004683021,0.001727015,0.9607856,0.0001384999,0.008466777,0.00001838808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993895,0.0004684681,0.003708842,0.00008186377,0.00005592423,0.00004238543,0.0002736652,0.00007465939,0.001399199],"genre_scores_gemma":[0.9931058,0.0003528714,0.003492392,0.0001591994,0.00002124901,0.00006097644,0.001043658,0.00009052839,0.001673399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001975711,"threshold_uncertainty_score":0.00660944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1633368387968907,"score_gpt":0.3208869037032377,"score_spread":0.157550064906347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}