{"id":"W2114820240","doi":"10.4049/jimmunol.1002320","title":"TLR1/TLR2 Agonist Induces Tumor Regression by Reciprocal Modulation of Effector and Regulatory T Cells","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Agonist; Effector; TLR2; Reciprocal; Regression; Modulation (music); Chemistry; Regression analysis; Cancer research; Cell biology; Internal medicine; Receptor; Biology; Medicine; Mathematics; Biochemistry; Physics; Statistics; Innate immune system; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001044935,0.0001426823,0.0003542028,0.0001478624,0.0001506233,0.000004288487,0.000261691,0.0002197463,0.0001233444],"category_scores_gemma":[0.0001122215,0.00008685639,0.00007601457,0.0000851326,0.0004999741,0.0001728884,0.00007554214,0.000407104,0.00003299821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002933207,"about_ca_system_score_gemma":0.00006352599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004987825,"about_ca_topic_score_gemma":0.000001200871,"domain_scores_codex":[0.9981966,0.0008789244,0.000597826,0.00008963911,0.00004821043,0.0001888053],"domain_scores_gemma":[0.9984479,0.0002573435,0.0008940663,0.0002362963,0.0001521498,0.00001227675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00332374,0.00006813769,0.0001216116,0.00001356388,0.0001894183,0.000002485224,0.001388868,0.000001177022,0.986975,0.0001022048,0.001206693,0.006607129],"study_design_scores_gemma":[0.001057644,0.0009542344,0.03559067,0.00009512062,0.00007402016,0.0004633342,0.000381595,0.00000249263,0.9590155,0.000249911,0.002027884,0.00008756211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878786,0.01072923,0.00009093954,0.0001199849,0.0008467226,0.0001243354,0.000003343591,0.000008985804,0.0001978815],"genre_scores_gemma":[0.9989945,0.0005723504,0.00005487706,0.00003424223,0.00002948927,0.000001748591,0.000006744118,0.00001175594,0.000294272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03546906,"threshold_uncertainty_score":0.3541901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01150285878579601,"score_gpt":0.2161074538884805,"score_spread":0.2046045951026845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}